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- The mouse bone marrow micronucleus test and the mouse sperm morphology test were used to evaluate genotoxicity of ATS. 采用小鼠骨髓细胞微核试验、小鼠精子畸形试验对其遗传毒性进行评价。
- Method Acute toxicity and accumulative toxicity tests,Ames test and bone marrow micronucleus test were in KM mice. 方法 采用昆明小鼠进行急性经口毒性实验、蓄积毒性实验、Ames实验以及骨髓嗜多染红细胞微核实验。
- Purpose and Methods: In order to characterize the antimutagenic effect of seaweed polysaccharides(SP), the mouse bone marrow micronucleus test and mouse sperm malformation test were conducted. 目的与方法:本文选用小鼠骨髓嗜多染红细胞微核试验和小鼠精子畸形试验,对海藻多糖的抗突变作用进行研究。
- GMA had positive results in Ames test and mouse bone marrow micronucleus test. GMA bound with DNA convalently, induced UDS and inhibited DNA replication in lymphocyte in vitro. GMA在Ames试验和小鼠骨髓微核试验得到阳性结果,GMA可与DNA共价结合,在体外淋巴细胞培养诱导UDS和抑制DNA复制。
- The result of mouse bone marrow polychromatic erythrocyte micronucleus test was negative. 对小鼠骨髓嗜多染红细胞微核试验结果为阴性。
- To use micronucleus test in bone marrow polychromatic erythrocytes of mice.?RESULTS? 经口给予蓝靛果汁的同时腹腔注射环磷酰胺,可使微核率呈剂量依赖性下降。
- Bone marrow cell micronucleus test and mice sperm abnormality test had negative results and there was no mutagenicity. 其小鼠骨髓细胞微核和精子畸形试验均为阴性,未显示出致突变性。
- By means of sister chromatid exchange method (SCE),micronucleus test of bone marrow cells, genetic toxicity of Coprinus comatus was evaluated in mice. 应用小鼠骨髓细胞姐妹染色单体交换(SCE)及微核试验对鸡腿蘑进行遗传毒理检测。
- MATERIALS AND METHODS: The oral acute toxicity test, micronucleus test of bone marrow PCE cell and sperm shape abnormality test were carried out. 材料与方法: 采用小鼠经口急性毒性试验、小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验。
- Objective To evaluate the mutagenicity of machinable bioactive glass ceramics (MBGC) by micronucleus test of bone marrow. 目的了解可切削生物活性玻璃陶瓷(MBGC)的潜在致突变性。
- MATERIALS AND METHODS:The oral acute toxicity test,micronucleus test of bone marrow PCE cell and sperm shape abnormality test were carried out. 材料与方法:采用小鼠经口急性毒性试验、小鼠骨髓嗜多染红细胞微核试验、小鼠精子畸形试验。
- MATERIAL AND METHODS: Chromosome aberration test,micronucleus test of bone marrow cell and sperm shape abnormality test in mice were used in this study. 材料与方法:采用小鼠睾丸染色体畸变试验,小鼠骨髓微核实验以及小鼠精子畸形实验方法。
- The mutation potential of ethephon was by investigated the micronucleus test of bone marrow polychromatophilic erythroblasts (PCE) cells and sperm shape abnormality test in mice. 摘要为测定乙烯利对人体健康的影响,采用小鼠骨髓细胞微核试验和小鼠精子畸形试验分别检测了乙烯利对小鼠体细胞和生殖细胞的致突变性。
- Micronucleus test showed that the micronucleus frequencies in mice bone marrow induced by 2-AAF increased significantly while PCE/NCE ratios declined significantly. 微核试验表明 2 AAF引起小鼠骨髓微核率明显升高 ,PCE/NCE比值下降。
- The mutagenicity of do-mestic Vesnarinone (OPC-8212) waw stud-ied by Ames test, micronucleus test ofNIH mouse bone marrow and chromosomeaberration assay in CHL cells. 作者应用鼠伤寒沙门氏菌回复突变试验,小鼠骨髓红细胞微核试验及CHL细胞染色体畸变试验,对维那利酮(OPC-8212)的诱变性进行了试验研究,其结果均为阴性。
- The mutagenicity of the secondary metabolites was studied by experiments including bone marrow micronucleus assay (stained by giemsa and feuglen) and ames assay. 通过骨髓微核试验(采用Giemsa和Feuglen两种染色方法观察微核)和鼠伤寒沙门氏菌回变试验这两大经典试验对豆类丝核菌次级代谢产物的致突变性进行研究。
- Simultaneous studies wereconducted on bone marrow micronucleus and spermatocyte chromosome aberration in mice, yielding negative resultsand no evidence of mutagenic effects. 同时报道了小鼠骨髓微核和睾丸精母细胞染色体畸变试验研究的结果,即两项试验均为阴性,无致突变效应。
- Methods : Micronucleus test in bone marrow PCE and chromosome aberration assay in primary spermatocyte were undertaken in mice exposed to the immersion. 方法:用香烟烟蒂生理盐水浸泡液为实验材料进行小鼠骨髓嗜多染红细胞(PCE) 微核试验和睾丸初级精母细胞染色体畸变试验。
- The potential genotoxicity of two chemical disinfectants on bion was detected with micronucleus test of vicia faba root tips cells. The results were compared with those effects on mice bone marrow cells. 本文用蚕豆根尖细胞微粒技术测定两种化学消毒剂对生物体的潜在遗传毒性,并用小鼠骨髓细胞微核作对比,两种方法测定的结果有一致的剂量效应关系,提示在处理病情施用消毒药物时,应考虑减少对环境的污染。
- Method: salmonella typhimurium mutagenicity test (Ames test), chromosome aberration (CA) test of cultivated cells of mammalian, micronucleus test in mice and mammalian bone marrow CA test were used. 方法:应用鼠伤寒沙门菌回复突变实验(Ames实验)、哺乳动物培养细胞染色体畸变(Chromosome Aberration, CA)实验、小鼠微核(Micronucleus, MN)实验和哺乳动物骨髓细胞CA实验。
