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- The finding of Neurotrophic Factors( NTF) bring about new hope for SCI. 神經營養因子(Neurotrophic Factors,NTF)的發現為脊髓損傷的治療帶來了新的希望。
- In the process of development and regeneration of nervous system, it act as neurotrophic factor. 在神經系統發育和再生過程中,肝細胞生長因子作為神經營養因子發揮作用。
- To date, the most potent of these chemicals is glial-cell-line deried neurotrophic factor (GDNF). 迄今為止,在這些化學物質之中效果最好的就是神經膠質細胞源性的神經營養因子。
- Objective To investigate the role of ciliary neurotrophic factor (CNTF) in injury of central neuron. 目的研究睫狀神經生長因子(CNTF)在中樞神經元抗損傷中的作用及機制。
- Objective To investigate the effects of glial cell line derived neurotrophic factor in human inflammatory pulp. 目的探討膠質源性神經營養因子(GDNF)在人炎症牙髓中的表達及意義。
- Objective To explore the changes of brain-derived neurotrophic factor(BDNF) after repeated febrile seizures (FS). 目的探討大鼠反覆高熱驚厥(FS)後腦源性神經營養因子(BDNF)的變化。
- In the process of development and regeneration of nervous system,it act as neurotrophic factor. 在神經系統發育和再生過程中,肝細胞生長因子作為神經營養因子發揮作用。
- Synaptic actions of brain-derived neurotrophic factor (BDNF) are "gated"by cAMP, but the underlying molecular mechanisms remain unclear. 腦源性神經營養因子(BDNF)的突觸活動受到環腺苷酸(cAMP)的門控調節,但是這種調節機制還不清楚。
- To study the ultr a structure localization of Schwann cell (SC) derived neurotrophic factor (SDNF) in Schwann cells. 目的觀察許旺細胞源神經營養因子的超微結構定位,探索其在神經、皮膚和肌肉中的分佈以及神經損傷前後量的變化。
- Ma ZC, Wu XL, Pan W, et al.Expression of brain-derived neurotrophic factor receptor trkB on NIH 3T3 cells[J].Life Sci Res, 2001, 5(3):265-9. [6]馬仲才;吳曉蘭;潘衛;等.;腦源性神經營養因子受體trkB在NIH 3T3細胞上的表達[J]
- Nerve growth factor is the typical representative of neurotrophic factor family,which has conspicuous effect on nervous system. 神經生長因子(NGF)是神經營養因子家族的典型代表,為一種鹼性蛋白,是神經系統中最重要的生物活性分子之一,有明顯的中樞效應。
- The second approach is based on animal studies showing that ciliary neurotrophic factor (CNTF) can protect striatal cells from death. 第二種治療方式是根據動物實驗的結果:睫狀神經營養因子(CNTF)能保護紋狀體神經元免於死亡。
- Objective To study the effect and mechanism of ciliary neurotrophic factor (CNTF) on the spinal motor neuron death and degeneration following peripheral nerve lesion in the rat. 目的探討周圍神經損傷后睫狀神經營養因子(CNTF)對脊髓運動神經元的保護作用及其作用機理。
- Objective To study the protective effects of Schwann cell derived neurotrophic factor (SDNF) on motoneurons of spinal anterior horn from spinal root avulsion induced cell death. 目的研究雪旺細胞源神經營養因子(SDNF)對臂叢神經根性撕脫所致前角運動神經元死亡的保護作用。
- Brain-derived neurotrophic factor (BDNF) was shown to induce antiapoptotic mechanisms after stroke and to reduce infarct size and secondary neuronal cell death. 腦源性神經營養因子(BDNF)被顯示了卒中后可誘導抗凋亡機制並減少梗塞面積以及繼發神經細胞死亡。
- Brain-derived neurotrophic factor (BDNF) is one of the neurotrophic factors.BDNF has many biological effects on neurons of peripheral and central nervous system. 摘要腦源性神經營養因子(BDNF)是神經營養因子家族中的一員,BDNF對周圍和中樞神經元有廣泛的生物學作用。
- Objective:To prepare stable, small-sized injectable sustained-release nanoparticles harboring brain-derived neurotrophic factor (BDNF) and to evaluate its drug releasing process. 目的:製備穩定性高、粒徑小的腦源性神經營養因子(BDNF)緩釋注射納米粒,並評價其釋葯過程。
- Kim H, Li Q, Hempstead BL, et al.Paracrine and autocrine functions of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in brain-derived endothelial cells[J]. 孫春艷,胡豫,吳濤,等.;多發性骨髓瘤細胞腦源性神經營養因子對血管新生作用的研究[J]
- Preincubation of the cultures with ciliary neurotrophic factor (CNTF) for 24 h promoted neuronal survival and decreased the LDH efflux and the level of NO induced by ionomycin. 提前24 h給予不同濃度CNTF, 均能提高神經元的存活率, 減少LDH漏出, 其作用呈劑量依賴性;CNTF可降低ionomycin引起的NO含量升高;
- To construct a recombinant plasmid containing protein transduction domain(PTD) and brain derived neurotrophic factor(BDNF) fusion gene and express in E. 構建含蛋白轉導結構域(PTD)與腦源性神經營養因子(BDNF)融合基因的質粒,並在大腸肝菌中表達。