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- CONCLUSION: Base pair substitution mutation and frame shift mutation were caused by folpet in Ames test.And DNA breakage in human PMNC might be induced by folpet. 结论: 灭菌丹可引起鼠伤寒沙门氏菌碱基置换和移码突变,并可能损伤人外周血淋巴细胞DNA的完整性。
- For example, achondroplasia, a common form of dwarfism, usually occurs as a result of a mutation at base pair 1138 in a gene called FGFR3 on the short arm of human chromosome 4. 举例来说,软骨发育不全症(achondroplasia,一种常见的侏儒症)通常是人类第四对染色体短臂上FGFR3这个基因的第1138个碱基对发生突变。
- In February, the two groups charting the human genome published their results--the entire 3 billion base pair sequence. 在(2001年)2月份,两个研究小组发表了他们的人类基因组图,也就是30亿碱基对序列结果。
- The base pair ratio, AT:GC, is constant within a species but differs between species. AT:GC之间的碱基比具有种内特异性,但在不同种之间往往是不同的。
- There are three million base pairs in human DNA. 人类基因组中有30亿个基对。
- Sequencing DNA has come down in price by half annually, from $10 per base pair in 1990 to under a penny today. 资讯科技通常不要一年,价格表现比和产能就会增加一倍。
- The binding of a series of square planar Pt(II) adducts on the Watson-Crick base pair AT and GC wasinvestigated using advanced quantum chemical method. 用量子化学方法研究一系列Pt(II)配合物作用于嘌呤碱基N7位点后对Watson-Crick碱基对AT、GC的影响.
- Ames test showed that both of the base pair transversion and frameshift mutant in DNA was not induced by irradiated starch. Ames试验也说明辐照淀粉不诱发DNA中碱基对的置换型和移码型突变。
- It base pairs with adenine in the complementary strand of DNA. 在互补DNA中的配对碱基为腺嘌呤。
- Conventional sequencers evaluate about 1,000 base pairs at a time. 传统定序仪一次约只能评估1000个碱基对。
- How long would it take for the E. coli RNA polymerase to synthesize the primary transcript for the E. coli genes encoding the enzymes for lactose metabolism (the 5,300 base pair lac operon)? 一般认为大肠杆菌RNA聚合酶合成大肠杆菌编码乳糖代谢酶(5300bp的乳糖操纵子)的基因的第一次转录要多长时间?
- Electrochemical detection of DNA hybridization usually involves monitoringof a current response, resulting from the Watson-Crick base pair recognition event, under controlled potential conditions. 将电化学活性良好的纳米金、银以及壳一核型合金纳米微粒,分别标记在疏基修饰的寡聚核昔酸片段上,制备成金属纳米微粒标记DNA电化学探针,通过与固定在电极表面的互补靶DNA杂交后,检测探针上标记物的电化学信号来识别和测定靶序列。
- Objective To study the association of the polymorphism of the 377 base pair of muscle glycogen synthase gene(GYS1)intron 14 with type 2 diabetes mellitus and complicated with hypertension in the middle-aged and elderly people of Tianjin. 目的研究天津地区中老年人群中肌糖原合酶基因(GYS1)内含子14第377bp多态性与2型糖尿病(2型DM)及其合并高血压的关系。
- Researchers have also advocated assessing health risks within ethnic groups based on inherited variations in just one DNA base pair. 研究人员也主张,仅仅根据一个DNA碱基对的遗传变异,就可以评估不同种族的健康风险。
- The human genome contains approximately three billion chemical base pairs. 人类基因组包含大约三十亿个化学碱基对。
- He invented a technique to determine the sequence of base pairs in dna. 他发明了一种技术来测定DNA的碱基对序列。
- Though 30 base pair deletion of Epstein-Barr virus LMP1 may not be an important pathogenetic step in extranodal nasal type NK/T-cell lymphoma, it may play some role in tumor progression. 不能简单地将LMP1缺失型作为结外鼻型NK/T细胞淋巴瘤的致病因素,但也不能完全否定其促进该淋巴瘤演进的作用。
- Strictly, a base pair is a pair of complementary bases (i.e. the A:T, G:C and A:U interactions) held together by hydrogen bonds. 严格地说,碱基对是一对相互匹配的碱基(即A:T,G:C,A:U相互作用)被氢键连接起来。
- These steps include specific cutting of DNA at defined sites, joining or splicing of DNA fragments, and numerous other modifications which allow manipulation down to the level of a single base pair. 这些步骤包括在DNA特异位点切割,连接和切断DNA片段和很多其它修饰直至对单个碱基对的处理。
- Pruitt of Purdue University study Arabidopsis whose petals are fused.Such plants have two mutant copies of a gene called hothead, which differ from the normal gene by a single base pair. Pruitt),研究一种花瓣黏合的阿拉伯芥品系,这些植物带有一对突变的hothead基因,这种突变基因中有一对碱基与正常的不同。