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- It has been hypothesized that destruction of biliary tract in primary biliary cirrhosis (PBC) would be closely correlated with proliferation of autoreactive T cell. 自身反应性T细胞的增殖与原发性胆汁性肝硬化(Primary biliary cirrhosis,PBC)中胆管特异性损伤密切相关,并在PBC的发生、发展中起重要作用。
- Objective Analyzing biological function of ATL, an autoreactive T cell line from lupus-prone mice BXSB to study the feasibility of TCV (T cell vaccine) in the SLE. 目的 探讨自身反应性T细胞系过继转移对受体小鼠免疫应答的影响 ,为在BXSB小鼠探索T细胞疫苗的可行性奠定基础。
- The study of autoreactive T cells in alopecia areata may help to elucidate... 研究斑秃自身反应性T细胞,有助于阐明斑秃的发病机制以及寻找有效及有针对性的治疗措施。
- Study of autoreactive T cells contributing to the pathogenesis of junior SLE and Rheumatoid Arthritis. 发展快速诊断小儿性红斑性狼疮及风湿性关节炎的方法。
- The immune regulation of autoreactive T cells involves in the idiotype anti-idiotypic regulatory network. 病理性自身反应性T细胞是多发性硬化、类风湿性关节炎等自身免疫病的主要致病原因。
- LP-CD4+OX40+T cells are a subset of autoreactive T cells stimulated by specific antigen in situ. Anti-OX40L MoAb can inhibit the proliferation response of this T cells. 结论:OX40在UC患者病变部位的LP-CD4+T细胞上表达明显增加,LP-CD4+OX40+T细胞是一类在原位被特异性抗原激活后扩增的T细胞,它们在UC的免疫病理机制中起重要作用。
- This review focuses on the mechanisms of autoreactive T cells escaping peripheral tolerance, migration from blood to hair follicles, and evidence that alopecia areata is mediated by T cells. 综述自身反应性T细胞逃逸外周耐受、从外周血向毛囊迁移,及其介导斑秃发病的证据。
- autoreactive T cell 自身反应性T细胞
- Both CD8+ and CD4+ autoreactive T cells display characteristic epitope recognition and recognize the same core epitope.Unlike CD4 autoreactive T cells; 更进一步的发现表明这种CD4和CD8细胞分别认知识别同一核心抗原上的不同表位。
- Autoreactive T cells 自身反应性T细胞
- Results We isolated, in the absence of a known stimulating antigen, a autoreactive CD4 + T cell line(ATL) and two T cell clones from BXSB mice. TCR TRBV2S1, TRAV5S1 and TRAV10S1 were used in ATL. T细胞系主要应用TRBV2S1、TRAV5S1和TRAV10S1,而 2个T细胞克隆均为TRBV2S1和TRAV10S1。
- T cell whether synthesize and secrete lymphatic factor? 细胞能否合成和分泌淋巴因子?
- Methods T cell clones were isolated by limiting dilution. 方法通过有限稀释法建立T细胞克隆。
- It promotes both humeral and cellular immunity, especially T cell immunity. 它促进肩和多孔的免疫, 特别是T 细胞免疫。
- Marrack P, Kapler L. The T cell receptor[J]. Science, 1987,238:1073. 谢蜀生.;血细胞嵌合体与移植耐受[J]
- Pure red cell aplasia with thymoma: evidence of T cell clone disorder. 胸腺瘤致单纯红细胞再生障碍机制的初步探讨。
- A lymphocyte that derives from the thymus and is the precursor of a T cell. 胸腺细胞一种由胸腺繁殖而成的淋巴细胞,是T细胞的前身
- Gamma delta T cells are part of the body's defenses. 伽马德耳塔T细胞是人体免疫系统的一部分。
- T cells in HUCB is a potential resource of adoptive immunotherapy. 脐血淋巴细胞经适当刺激可以活化 ,有望用于过继性免疫治疗
- Tk + T cells were sensitive to GCV (P<0.05),but not to ACV(P>0.05). 转染HSV-tk T细胞(tk+T细胞)对GCV有敏感性(P<0.;05);而对ACV不具有敏感性(P>0
