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- COX-2 is a key enzyme that converts arachidonic acid to PGs. COX-2是前列腺素(PGs)生物合成的限速酶,许多癌前病变和恶性肿瘤存在其基因的扩增及蛋白的高表达。
- Study on Arachidonic Acid Mutation Strains Breeding of Diasporangium sp. 轮梗霉高产花生四烯酸的诱变育种研究。
- The ethanol stress was applied to enhance arachidonic acid (AA) production. 利用乙醇胁迫作用提高花生四烯酸(AA)产量。
- Effects of Metal Ions Addition on the Growth of and Arachidonic Acid Production by Diasporangium sp. 六种金属离子对轮梗霉生长及产花生四烯酸的影响。
- Cyclooxygenase is the rale-limiting enzyme in the synthesis of PGs from arachidonic acid. 环氧化酶(Cyclooxygenase,COX)是花生四烯酸(Arachidonic Acid,AA)合成各种内源性前列腺素(PGs)过程中的限速酶,其催化产生的PGs参与机体的多种生理及病理过程,如发热、炎症、出凝血机制等。
- Lipoxygenase (5LOX) is a key enzyme critical for leukotriene synthesis from arachidonic acid. 5脂氧酶(5LOX)是催化花生四烯酸形成白三烯的关键酶。
- Arachidonic acid was a kind of essential polyunsaturated fatty acid for human with great health function. 花生四烯酸是一种人体必需的多不饱和脂肪酸,具有极高的保健价值,目前已经受到了人们的广泛关注。
- Aspirin resistance was analyzed by examination of blood platelet aggregation induced by adenosine diphosphate(ADP) and arachidonic acid (AA). 服用阿司匹林100mg/d,连服7天,分别以二磷酸腺苷(ADP)和花生四烯酸(AA)为诱导剂,检测入选患者的血小板聚集率。
- In the first 6 months of life, the formula-fed group was randomly assigned to formula with or without supplementation with DHA or arachidonic acid. 在出生后的6个月内,在配方奶喂养组的配方奶中随机添加和不添加DHA或花生四烯酸。
- Thrombosis was caused by thrombosis instrument in vivo. Platelet aggregation was induced by ADP, arachidonic acid and collagen, respectively. 以体内血栓形成仪刺激大鼠血栓形成,二磷酸腺苷(ADP),花生四烯酸及胶原诱导血小板聚集,测量血栓形成时间和血小板聚集抑制百分率。
- A strain of Diasporangium sp. containing arachidonic acid (AA), ei cosapentaenoic acid (EPA) and acid(GLA) at the same time was c hosen. 研究结果表明,有利于获得最大菌丝产量的条件为:黄泔水稀释5倍、添加20g/L葡萄糖、0g/L氮源、培养8d。
- Abstract : Objective:To investigate the role of arachidonic acid metabolism in Crohn’s disease complicated by intestinal fistula. 摘要 : 目的:探讨花生四烯酸代谢在克罗恩病并发肠瘘病理机制中的作用。
- Methods:The inflammatory edema reaction of rat paw was induced by a subcutaneous injection of arachidonic acid(1.0 g/L,0.1 mL)and histamine(10 g/L,0.1 mL)respectively. 方法:给大鼠左、右爪分别皮下注射花生四烯酸(1.;0g/L;0
- Moreover, increased breakdown of arachidonic acid results in increased production of proinflammatory lipid mediators like prosta glandines, thromboxanes and leukotrienes. 甚至进一步,引起花生四烯酸降解的增加导致前炎症脂质介质如前列腺素、血栓素和白三烯等的形成增加。
- The maximam platelet aggregation rates by four different agonists(Adenosine diphosphate,Epinephrine,Collagen,Arachidonic acid)increased significantly in control group dogs. 长期心房快速起搏使对照组犬二磷酸腺苷、肾上腺素、胶原和花生四烯酸诱导的血小板最大聚集率较起搏前明显增加,缬沙坦能够部分抑制起搏引起的血小板激活。
- Current studies indicate that the anticarcinogenic functions of CLA can be attributed to the ability to inhibit the synthesis of eicosanoids derived from arachidonic acid. 研究表明,共轭亚油酸的抗癌作用可归结为抑制衍生自花生四烯酸的类二十烷合成的能力。
- The main metabolism pathways of arachidonic acid catabolism and the corelation between metabolic products and inflammation were concluded based on a large amount of literature. 通过对大量文献的调研,总结了花生四稀酸代谢的主要途径,以及代谢产物与炎症发生和发展的关系。
- Abstract: Cyclooxygenase (COX) is a rate-limiting enzyme which catalyzes arachidonic acid to produce prostaglandin and thromboxane.There are 3 isoenzymes,COX-1,COX-2 and COX-3. 摘要: 环氧化酶是催化花生四烯酸生成前列腺素和血栓素的限速酶,有环氧化酶1、环氧化酶2、环氧化酶3共三种同工酶。
- They proposed that DHA release from plasma lipid (PL)may interfere with arachidonic acid (AA)metabolism or that DtIA may alter membrane properties and subsequent enzyme activities. 他们认为血脂中DNA的释放可能干扰了花生四烯酸(AA)的代谢,或者DNA可能改变膜的性质及酶反应过程。
- Using turbidimetry,we found that API0134 markedly inhibited adrenalin (Adr)-,adenosine diphosphate(ADP)-,arachidonic acid(AA)and collagen(Coll)-induced platelet aggregation both in vivo and in vitro. 采用比浊法观察到API0134显著抑制二磷酸腺苷(ADP)、肾上腺素(Adr)、花生四烯酸(AA)和胶原(Coll)诱导的人和大鼠血小板聚集。