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- Preclinical studies have shown that PDT of Tumor auguments the host specific antitumor immune response. 许多动物实验表明，PDT治疗后，机体产生了特异性抗肿瘤免疫反应。
- Tumors are immunogenic, the immune system recognize tumors through mechanical immune surveillance, generate specific antitumor immune response to inhibit the growth of tumor. 肿瘤具有免疫原性，机体通过精细的免疫监视机制识别肿瘤，并能够产生特异性的抗肿瘤免疫反应，从而抑制肿瘤的生长。
- BACKGROUND Cell-mediated immunity dominate the antitumor immune response, antigen-specific cytotoxic T lymphocytes(CTL) are the major effector cells. 背景知识 肿瘤免疫以细胞免疫为主，抗原特异性细胞毒性 T淋巴细胞（CytOtoXIC T lymphocyte， CTL）是重要的效应细胞之一。
- Objective: To investigate the role of T cell in the antitumor immune responses induced by MIF gene-modified tumor vaccine. 目的：研究T细胞在巨噬细胞游走抑制因子（MIF）基因修饰的瘤苗诱导抗肿瘤免疫反应中的作用。
- Viral infection and amplification eventually induce cancer cells into cell death pathways and elicit host antitumor immune responses. 病毒的感染和增殖导致癌细胞死亡,并诱发宿主抗肿瘤免疫反应而进一步清除癌细胞。
- Another approach taken to raise antitumor immune responses has been to usecytokine-expressing tumor cells as vaccines, which in turn have paracrine effects on Tcells or APCs. 另一个重要的提升T细胞抗肿瘤免疫反应的策略是以分泌细胞因子的肿瘤细胞作为肿瘤疫苗，通过对T细胞和APC产生旁分泌效应，达到抗肿瘤的目的。
- It is critical in antitumor immune responses that the APCs (antigen presenting cells) present tumor antigens(Tags) to T cells to activate immune system to eradicate tumor cells. 抗肿瘤免疫应答中关键的一步是抗原递呈细胞(APC)将肿瘤抗原递呈给T细胞，激活机体的免疫系统来清除肿瘤细胞。 树突状细胞(DC)是目前认为功能最强的抗原递呈细胞，也是APC的一个独特的亚群。
- Over the years there had been scattered reports that PDT not only destroys tumors locally but also evokes antitumor immune responses that target and attack distant metastases. 在过去的几年中一些零散的关于PDT的报道称，PDT不仅可以在局部破坏肿瘤，还可以引发机体的抗肿瘤免疫反应以阻止肿瘤的远处转移。
- Objective: To study the role of MIF gene modified FBL3 erythroleukemia cells (MIF FBL3) in the induction of antitumor immune responses in vivo . The biologic characteristics of MIF FBL3 cell were investigated. 目的 :研究巨噬细胞游走抑制因子 (MIF)基因修饰的 FBL 3红白血病细胞的生物学性质变化 ,为探讨其体内诱导抗肿瘤免疫反应的作用奠定基础。
- Conclusion: It is suggested that MIF gene-modified tumor vaccine can induce specific antitumor immune responses mediated by T cells and may be a candidate for gene therapy of tumor. 结论：MIF基因修饰的瘤苗能诱导T细胞介导的抗肿瘤免疫反应，有可能作为肿瘤基因治疗的候选者。
- These cells can prevent autoimmune diseases,regulate the antitumor immunity and play a crucial role in suppressing immune responses to inflammation and transplantation. 它能够抑制自身免疫病的发生,参与肿瘤免疫的调节,在感染和移植免疫中也发挥着重要作用。
- In vitro antitumor immune response induced by fusion of dendritic cells and Ewing's sarcoma cells 树突状细胞与尤文肉瘤细胞融合诱导肿瘤免疫应答的体外研究
- Induction of Active Antitumor Immune Response by Myeloma Idiotype Protein-pulsed Dendritic Cells 骨髓瘤独特型抗原致敏树突细胞诱导的主动免疫反应
- The Experimental Study on Idiotypic DNA Vaccine against Human B-cell Lymphoma to Induce Antitumor Immune Response 人B细胞淋巴瘤独特型DNA疫苗诱导抗肿瘤免疫反应的实验研究
- Mechanisms of NKT Cells in Antitumor Immune Response with Promotion or Suppression Effect NKT细胞抑制或增强抗肿瘤免疫反应的机制
- Genetically Modified Myeloma Cell Vaccine Inducing Antitumor Immune Response in vivo 多发性骨髓瘤基因修饰瘤苗诱导体内抗肿瘤反应的实验研究
- Study of Specific Antitumor Immune Response Induced by pcDNA3.1/HSP70-MAGE-3 Fusion DNA Vaccine pcDNA3.;1/HSP70-MAGE-3融合DNA疫苗诱导特异性抗肿瘤免疫应答的实验研究
- The experimental research on antitumor immune response of tumor-bearing mice by S-180 tumor cells and BCG vaccines S－180瘤苗联用BCG治疗效应的研究
- An innate, acquired, or induced inability to develop a normal immune response. 免疫缺陷先天的、后天的或诱发的正常免疫反应能力的缺失
