您要查找的是不是：
- We observed the effect on proliferation and growth of human hepatoma cell by using c-myc antisense ODN in vivo and in vitro,and studied its mechanism. 本研究针对c-myc mRNA第二外显子起始码AUG及其下游四个密码子设计合成了反义、正义和错配的寡核苷酸，在体外和体内两个方面，对人肝癌细胞SMMC-7721的生长、增殖作用进行了观察，并初步探讨了对其作用机制。
- Methods The synthesized modified antisense ODNs were added to the pancreas cancer cell lines Aspc-1 and Bxpc-3 respectively by gene pluser electroprotocal, telomerase activity was tested by RT-PCR-ELISA, and the cell number were compared by MTT. 方法 人工合成端粒酶反义寡核苷酸片段,电转移法将反义端粒酶序列导入胰腺癌细胞株Aspc-1、Bxpc-3中,RT-PCR-ELISA法检测端粒酶活性,MTT法检测细胞活性。
- antisense ODNs 反义寡核苷酸
- Antisense IRAK 2 ODN blocked IRAK 2 mRNA translation and protein expression was inhibited. 反义IRAK 2寡核苷酸可阻断IRAK 2mRNA的翻译 ,从而抑制IRAK 2蛋白的表达 ,抑制率达45%25 ;
- The antisense drug synthesized by DNA synthesizer is an oligodeoxynucleotide (ODN). 由机器合成的反义核酸药物需要有效的纯度鉴定方法。
- Antisense oligodeoxynucleotides (ASODNs) are synthetic ODNs, which hybridize with specific gene segments modulating the expression of these genes at transcriptional and translational stages. 反义寡核苷酸（ASODN）是一段能与特定基因结合并抑制其表达的人工合成的脱氧寡核苷酸链，可在转录、翻译水平调节相关基因表达。
- Cell cycle analysis showed a significant decrease in S phase and a remarkable increase in G1/G0 fraction after exposure to antisense EGFR ODN in comparison with missense oligonucleotide-treated cells at the corresponding time. 细胞周期分析EGFR反义ODN作用于细胞后,细胞G0/G1期细胞数明显增多,S期细胞数相应减少,而G2+M期细胞数亦明显减少。
- Objective To investigate the efficacy of autologous bone marrow transplantation(ABMT) for patients with chronic myelogenous leukemia(CML) after in vitro purging of the graft with bcr/abl antisense oligodeoxynucleotides(AS ODN). 目的 观察bcr/abl反义寡核苷酸 (AS ODN)净化后自体骨髓移植 (ABMT)治疗慢性粒细胞白血病 (CML)的疗效。
- I focus on the role of antisense RNAs in plasmid replication. 本文着重叙述反义RNA在质粒复制中的作用及其进展。
- We used mouse germinal vesicle stage oocyte cultured with special concentration progesterone, or/and antisense c-myb ODN, or/and dbcAMP, or/and Verapamil, or/and heparin for 24h, and observed oocyte maturation and analysed the relationship between them. 在适宜浓度孕酮存在下,将小鼠GV 期卵母细胞或/和反义c-myb ODN、或/和二丁酰环腺苷酸(dbcAMP)、或/和维拉帕米(Verapamil)、或/和肝素钠(Heparin)共同孵育24h,观察卵母细胞体外成熟的情况并分析它们之间的相互关系。
- CpG-N ODN could inhibit the surface binding and internalization of CpG-S ODN. CpG-N ODN对CpG-S ODN在hPBMC细胞表面的结合和内化具有抑制作用。
- Some CpG motifs and CpG ODN are potential activators of human immune cells. 人免疫细胞中存在有高度免疫刺激活性的CpG基序和CpG ODN。
- Applying antisense oligonucleotide to block the expression of CLC-3 mRNA. 应用反义核酸的阻断CLC一3 mRNA在细胞中的表达。
- Objective:In order to explore the effects of CD40 antisense RNA on Balm cell. 目的：探讨CD40反义RNA对Balm细胞的影响。
- Meanwhile, the application of antisense gene technology is prospected. 并对反义基因技术的应用进行了展望。
- Cyclin D3 antisense oligodeoxynucleotides were used in in vitro culture study. 用反义技术和流式细胞术研究周期蛋白D3在白血病细胞增殖中的作用。
- However, the molecular mechanism of this antisense regulation remains unknown. 然而这种反义调节的分子机理还不甚明了。
- Antisense oligodeoxynucleotides(ODN) 反义寡聚核苷酸
- Objective To study the immunotherapy role of CpG ODN(CpG oligodeoxynucleotide)on tumor. 目的探讨合成含CpG基序的寡核苷酸(CpG ODN)在肿瘤免疫治疗中的研究。
- TRE ODN treatment could inhibit obviously the IL-3 mRNA expression induced by PHAITPA stimuli. （3）TREODN处理则显著抑制PHA/TPA诱导的IL－3mRNA表达。
