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- This is most effective if a specific receptor blocking agent is available to counter the effects of a given agonist. 在这方面最有效的是利用特效的受体阻滞药对抗特定激剂的作用。
- Methods we detected the changes of antigen specific AFC and sIgA in in- testinal mucosa by ELISPOT and ELISA assay. 方法采用 ELISPOT 和 ELISA 法检测了胃粘膜、PP 结抗原特异性形成细胞(AFC)和小肠粘液 sIgA。
- MethodsThe changes of antigen specific AFC in gastric and intestinal mucosa were detected by ELISPOT assay. 方法采用 EL ISPOT法检测了胃粘膜、肠粘膜相关淋巴组织 PP结抗原特异性形成细胞 (AFC)。
- An antigen specific test showed that the recombinant did not have any cross-reaction with chicken H5 and H9 anti-sera. 抗原特异性试验证明,重组HA1蛋白与鸡H5、H9亚型AIV抗血清不发生交叉反应。
- Autoantibodies of AIHA have blood type antigen specificity. 自身免疫性溶血性贫血(AIHA)的自身抗体具有血型抗原特异性。
- Known vasoactive substance blockers could not alter the effect of AHF on BP. These data indicated that the effect of AHF on BP might be mediated via a specific receptor. 多种已知的血管活性物质的特异受体拮抗剂只能阻断其相应的血管活性物质对血压的作用，对AHF的降压活性无影响。
- These results indicated that normal cells have a highly specific receptor for LDL and that this receptor was defective or missing in cells from patients with FH. 这些结论表示出正常细胞有一个LDL的高特异性的受体，这个受体在有缺陷的或者在FH病人的细胞中丢失。
- Tumor antigen specific CTLs may prevent metastasis in the LCI-D20 model and prolong the survival time. 肿瘤抗原特异性CTL可以预防LCI-D20模型肝癌发生转移,延长动物存活时间。
- After binding to the specific receptor, EPO activates several signal transduction pathway downstream and protect the hypoxia nerve tissue by multi-pathway. EPO还对缺血缺氧神经系统具有保护作用并具有临床应用前景。
- Leptin is encoded by the obese gene.It is mainly acts via a specific receptor located in the hypothalamus to decrease appetite and increase energy expenditure. 瘦素是肥胖基因编码的一种蛋白质产物,通过与其受体结合发挥抑制食欲、减少能量摄入、增加能量消耗的生物学作用。
- In ABM, the remarkably increased expression of co stimulatory molecule CD86 in CD3 - MNC may enhance the anti tumor effect of antigen specific CTLs. ABM中CD3-细胞表面共刺激分子CD86表达明显增加 ,与ABM中特异性细胞毒性T淋巴细胞(CTLs)的生成有关。
- Antigen specific immune tolerance is induced in a mammalian host by administration of a toleragen in combination with a regimen of immunosuppression. 通过施用耐受原与免疫抑制方案相组合诱导哺乳动物宿主中的抗原特异性免疫耐受。
- BCG-CpG-DNA increased the anti-HBs neutralizing antibody level,promoted the production of antigen specific IgG2a,induced Th1 immune response,and partially reversed Th2 response. BCG-CpG-DNA能提高抗-HBs中和抗体水平,促进抗原特异性IgG2a的产生,诱导Th1型免疫应答,与铝佐剂协同作用能部分逆转Th2反应。
- Internationa Diabetes: On the issue of antigen specific prevention therapy for type I diabetes， which in your opinion is more involved， the auto-antibody or auto-reactive cells? 国际糖尿病：您提到1型糖尿病抗原特异性的预防措施，您认为是自身免疫抗体重要还是自身免疫细胞重要？
- Cancer vaccinologists often compare their field with that of monoclonal antibodies a decade ago, when those molecules that can, say, block a specific receptor on a cell had fallen into disrepute. 癌症疫苗学家经常把他们的研究领域比做10年前的单株抗体；单株抗体这种分子能够阻断某个变坏细胞上头的特定受体。
- The breast cancer antigen specifically combined with M4G3 McAb has 48,000 dalton molecule weight. 与M4G3单抗结合的乳腺癌抗原分子量约为48，000 dalton。
- Dendritic cells (DCs) are the most potent antigen presenting cells (APCs) that prime naive T lymphocytes and active antigen specific cytotoxic T lymphocytes(CTLs), which makes DC a promising tools for immunotherapy of cancer . 树突状细胞(Dendritic Cells,DCs)作为功能最强的抗原提呈细胞，在恶性肿瘤的免疫治疗中起着重要的作用。
- The mature DCs were co-cultured with autologous T cells to obtain antigen specific CTL (Ag-CTL) and antigen non-specific CTL (non Ag-CTL). The phenotypes of Ag-CTL were analyzed by flow cytometry. 成熟DCs与自体T细胞共育,分别获得Ag-CTL及non-Ag-CTL,流式细胞仪检测Ag-CTL细胞表型的变化;
- A further advantage is that, with varies of plant expression systems being used, the level of expression and immunogenicity of antigen specific proteins have been improved success... 而且,植物表达体系进一步多样化,抗原蛋白的表达量和免疫原性得到很大的提高。本文就这些进展进行了综述。
- Results: After 4 rounds of panning,20 positive clones were obtained and 18 clones were found to be able to bind keratin antigen specifically. 结果： 经过4轮筛选，获得20个能与角蛋白结合的阳性克隆，其中可产生特异性抗角蛋白抗体的克隆18个。
