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- One of the exactly questions to treat CHB is how to enhance the antigen presentation function of DC. 如何恢复或加强DC的抗原提呈能力,充分发挥机体免疫功能已成为治疗CHB急需解决的问题之一。
- The MR has been implicated in homeostatic processes, pathogen recognition and antigen presentation. 甘露糖在维持内环境稳定方面发挥作用,同时还有识别病原体和抗原递呈功能。
- B7 transfected CHO cells were used as artificial antigen presentation cells (APCs) in MLR to exclude the effects of other costimulatory molecules. 为了排除其它粘附分子的作用 ,应用联合转染DR7或 (和 )B7分子基因的CHO细胞系作为人工抗原递呈细胞 (APC)介导混合淋巴细胞反应 (MLR)。
- Cytotoxic T lymphocyte (CTL) responses、activated by HLA antigen presentation、are implicated in the control of HIV replication. 人类白血球抗原激发的T淋巴细胞与HIV病毒的复制有关连。
- They are highly expressed in a variety of tumors and are important in the anti-tumor actions of chemotherapeutic agents and antigen presentation. 它在多种肿瘤细胞中呈高表达,对肿瘤细胞的抗化疗药物的性质及抗原表达有重要意义。
- DC/C6 fusion cells had the ability of antigen presentation and activating T lymphocytes effectively. CD8+T lymphocytes play an important role in antitumor immunity. DC/C6融合瘤苗能够有效的发挥抗原提呈、活化T淋巴细胞的功能,CD8+T细胞参与抗胶质瘤免疫反应。
- Conclusion The transfection of the GM-CSF plasmid in vivo could stimulate the proliferation of the pre DC of bone marrow, and enhance antigen presentation of DC. 结论GM-CSF质粒体内注射可以明显刺激诱导小鼠髓源性DC前体的增殖,增强DC的抗原提呈作用。
- This article reviews AC133 about its structure of gnen and protein,transcriptional control,antigen presentation,biological function and application future. 本文从基因及蛋白结构、转录调控、抗原表达、生物功能以及应用前景等方面进行综述。
- Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development. 泛素-蛋白酶体通路介导细胞蛋白质的降解,在细胞周期、基因转录及表达、抗原提呈和炎症演进等方面发挥调控作用。
- AIM: To observe the dynamic changes in human leukocyte antigen DR (HLA-DR) antigen presentation on peripheral blood lymphocyte (PBL) of patients with postoperative pneumonia after renal transplantation and the curative efficacy of compound Qingrekeli. 目的:观察肾移植术后肺炎患者外周血淋巴细胞表面HLA-DR抗原表达的动态变化及中药复方清热颗粒的治疗效果。
- DC-SIGN is expressed in KG_1 and KG_1 derived DLCs, and the expression will increase after treatment by PMA and ionomycin,which provides an cell model for further study of antigen presentation mediated by DC-SIGN. KG1细胞和其来源的DLCs上均有DC-SIGN的表达,且在诱导为DLCs后DC-SIGN的表达增强,为进一步研究DC-SIGN介导的抗原呈递途径奠定了基础。
- In vitro antigen presentation assays, in vivo administration of the bromodeoxyuridine coupled to flow cytometry assays assessed intra-islet T cell activation in the absence or presence of B cells. 离体实验测定抗原呈递活性;在体动物实验,用溴脱氧尿苷处理后以流式细胞术检测B细胞(存在或不存在时)对胰岛内T细胞活性的影响。
- Because thymic dendritic cells are the potent antigen presenting cells in the thymus, they must play an important role in thymic negative selection. 胸腺树突状细胞作为胸腺内功能强大的抗原呈递细胞,在阴性选择中必定发挥着不可忽视的作用。
- Relationship between costimulatory molecule CD80/CD86 expressing on antigen presenting cells and spontaneous abortion. 抗原递呈细胞表面共刺激分子CD80/CD86表达与自然流产的关系
- Dendritic cells (DCs) are one of the most potent antigen presenting cells (APCs). 树突状细胞(DC)是目前已知的功能最强的专职抗原提呈细胞。
- HLA-DR~+ antigen presenting cells(APC) reduced remarkably in the SARS spleen white pulp. 脾白髓中HLA-DR+抗原呈递细胞明显减少。
- Dendritic cells are the most powerful antigen presenting cells,which plays very important effect in immune system. 树突状细胞是体内最强的抗原呈递细胞,在免疫系统中发挥着重要的作用。
- The first signal is specific, which T cell receptor could recognize and bind MHC molecule by antigen presenting cells. 第二信号是由T细胞上的CD28与抗原呈递细胞上的B7分子的结合而提供的。
- If antigen present cells (APCs) provide MHC-peptides only, do not present costimulatory signals such as CD80 and CD86 to T lymphocytes at the same time, T lymphocytes will became anergy, immune tolerance will be induced. 如果抗原提呈细胞(antigen present cell,APC)只提供MHC-抗原肽复合物而不提供CD80、CD86等共刺激信号,将使淋巴细胞无能,诱导免疫耐受。
- As we all know, antigen recognition. procession, presentation and T cells pulsing and activating all rely on the participationof antigen presenting cells (APCs). 抗原的识别、加工、提呈以及T细胞的致敏、激活和扩增都依赖于抗原递呈细胞(APCs)的参与。