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- alternative splicing factor(ASF) 可变剪接因子
- alternative splicing factor 可变剪接因子
- In fruit flies, for example, alternative splicing regulates the sex-determination pathway. 举例来说，果蝇性别的发育，就经由选择性剪接调节。
- Alternative splicing determines how the DNA is chopped into pieces and then reassembled. 选择剪切是遗传复制过程中的一个重要组成部分。
- The alternative splicing is regulated by the interaction between diverse cis-acting elements and trans-acting factors. 选择性剪接过程受多种顺式作用元件和反式作用因子相互作用调节。
- Objective:To explore the distribution of splicing factor SC35 in thymus in rats. 目的:观察剪接因子SC35在大鼠体内重要器官内分布情况。
- Results: Most of cells containing the splicing factor SC35 or SC35-like protein were in the thymus. 结果:胸腺内大部分细胞内含有SC35或SC35类蛋白,而在肝和肾内未发现有标记。
- Calcitonin gene-related peptide (CGRP) composed of 37 amino acids by alternative splicing of messenger RNA transcript of calcitoini gene. 降钙素基因相关肽(Calcitonin gene-related peptide,CGRP)是由降钙素基因编码的mRNA选择性拼接后转录而成的37个氨基酸组成的单链多肽，是全身最主要的扩张血管的神经活性多肽。
- With the fast development of bioinformatics,all kind of relevant database are keeping appearing,one of which is The Alternative Splicing Database(ASD). 在生物信息学的飞速发展中,与之相应的各种类型的数据库不断涌现,选择性剪接数据库(Alternative Splicing Database,ASD)便是其中之一。
- Alternative splicing of transcripts of transmembrane proteins, including N-CAM, is know to occur, resulting in different isoforms of the protein. 如改变此穿膜性蛋白基因(包括N-CAM)之转录本，会产生同功蛋白。
- The splicing factor SC35 or SC35-like protein in the nucleus of thymus cells had a few of speckles,but it accumulated near the membrane of nucleus. 金颗粒主要分布在细胞核的染色质间区和染色质周边及核仁的致密纤维组分区中。
- Bioinformatics is a new subject for the study of alternative splicing, especially for its regulatory mechanism, prediction and origin. 因此，研究基因选择性剪接是一项十分重要的工作。
- In this study, we have identified a novel alternative splicing isoform of the RTN gene family, RTN3-A1, which contains an additional 2.3-kb exon. 在本研究中，我们确认了RTN3基因的一个新的转录本，RTN3-A1。它包含了一个以前所发现的RTN3转录本所不具备的新的长2.;3 kb的内含子。
- A heuristic algorithm for multiple alignment was developed to more effectively study alternative splicing patterns of eukaryotic genes. 为对真核基因的选择性剪接形式进行准确、快速、有效的研究,提出了一种启发式多序列比对算法。
- Since RNA splicing factor might interact with HCV 3’NCR and be required for viral RNA synthesis, human small nuclear ribonucleoprotein U2B was chosen for further study. 基于RNA剪接因子可能与HCV 3'NCR相互作用、调节HCV复制的推测，本研究进一步探讨了剪接因子U2B蛋白在HCV基因复制中的作用。
- The alternative splicing is also a co-transcriptional process.Promoters can regulate alternative splicing and produce different mRNA isoforms. 选择性剪接也是1个伴随转录发生的过程，不同的启动子可调控产生不同的剪接产物。
- In this paper we briefly review the main method of identify alternative splicing is RT-PCR,Bioinformatics,Exon microarray. 本文简要综述了检测选择性剪接的主要方法:RT-PCR,生物信息学方,以及生物芯片的进展。
- In keeping with that idea, DNA sequences at the intron-exon junctions where alternative splicing occurs are often resistant to change during evolution. 有一个观察到的现象和这个观点相符：插入子和表现子的接点，也就是选择性剪接发生之处，在演化过程中通常鲜少改变。
- Researchers in the UIC College of Pharmacy found that interfering with the production of a splicing factor can inhibit the growth and inasieness of tumor cells in test-tube experiments. 芝加哥伊利诺大学药学院的研究人员发现在试管实验中抑制剪接因子的合成可阻断肿瘤细胞的生长与侵袭。
- The researchers discovered this transition in cancer cells when they observed an error in "alternative splicing," a key element of the genetic copying program inside cells. 科学家们通过在观察选择剪切时发现的一个错误，在癌细胞中发现了这种转变。
