..The diapause bioclock protein of Bombyx silkworm is count down clock which depends on esterase A4 (EA4), EA4 is the first confirmed time interval measuring enzyme.

• 家蚕滞育生物钟是依赖卵内酯酶A4(EA4)蛋白的倒计时型生物钟。EA4是最早被确认的具时间间隔测定功能的酶。