We found that, while induced the increase of WPB release by 3-fold in HAEC, thrombin (1 unit, 30 min) resulted in the increase of activation of Rac-GTP binding activity by 3.5-fold, and increase of ROS production by 3.4-fold.

• 凝血酶 (1单位 ,30min)介导WBP释放增加 (较基础值增加了 3倍 )的同时 ,使Rac GTP结合活性及ROS分别增加了 3 5倍和 2 4倍。