We detected penicillin(BPO,6-APA,BPE)specific IgE by ELISA with mono-clonal antibodies(McAb)and biotin-avidin system(BAS),and discussed its clinical signifi-cance.

• 利用单克隆抗体及生物素－亲和素放大系统检测青霉素抗原特异性IgE，并探讨其临床意义。