Usng the IUPAC preferential ordering scheme, each compound of animal carcinogenicity data base was placed into 13 classes respectively. The validation of 17 genotoxicity tests as predictors of animal carcinogenicity for each chmical class was evaluated.

• 本文按IUPAC化学结构分组法,将动物致癌性数据库资料分为13个组,分别评价了17种重要遗传毒理学试验对不同化学结构组别的预测致癌性的可靠性。