Type II FUS-CHOP mRNA expression was successfully detected in 20 of the 39 MRCLs cases (51.3%) positive for PGK mRNA expression, and no type I FUS-CHOP mRNA was detected, whereas 60 cases of control tumors were all negative for FUS-CHOP gene expression.
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- 对照组60例肿瘤标本均未检出FUS-CHOP融合基因表达。 采用长距离PCR技术,在9例黏液型/圆细胞型脂肪肉瘤新鲜标本中扩增出FUS-CHOP、EWS-CHOP基因组DNA序列(其中FUS-CHOP型7例、EWS-CHOP型2例),其中6例成功进行了序列测定。