Topical treatment with IL-lra has more significantly positive effect in promoting corneal allograft survival through Fas/FasL pathway than CsA treatment.

• CsA和IL一lra均可通过影响角膜植片细胞凋亡及Fas邝asL蛋白的表达发挥免疫抑制作用，且IL一lra免疫抑制作用明显优于CsA。