This study is to explore the relationship between the multi-gene type of estrogen receptor (ER), vitamin D receptor (VDR) and BMD, and the multi- gene type of ER and VDR effect on osteoporosis in healthy menopause women.

• 目的 从分子生物学水平探讨绝经后健康妇女雌激素受体(estrogen receptor，ER)、维生素D受体(vitamin D receptor，VDR)基因多态性对骨密度的影响，分析ER和VDR基因多态性对骨质疏松症的作用，为骨质疏松症的早期诊断和临床基因治疗提供理论基础和依据。