This model provides insights into the consequences of constitutive signaling by an oncogenic tyrosine kinase on hematopoietic progenitor quiescence, function, and cell fate.

• 该模型为研究类似于原癌基因酪氨酸激酶对于造血干细胞的静止、活动以及存活作用这样的组成性信号传导作用机制等提供了新的方向。