The in vivo binding and functional relation between BRCA2 and FHL2 was demonstrated by coimmunoprecipitation, mammalian twohybrid assay and luciferase detection.

• 免疫共沉淀和哺乳动物细胞双杂交试验显示BRCA2和FHL2在体内特异性结合，并证实FHL2在体内形成同源二聚体；