The NTFs are imperative to the survival, growth and differentiation of important neuronal populations in the peripheral and central nervous systems.

 
  • NGF必须与高亲和力受体TrkA结合才能发挥作用,通过一系列细胞内的信号传导途径影响靶细胞的生长,凋亡,分化和侵袭潜能。
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