Studies suggest that OCP treatment does increase insulin resistance, which is not only present in PCOS, but to some extent in other androgen excess diseases such as congenital adrenal hyperplasia.

• 研究显示口服避孕药的确可以增大胰岛素抵抗，胰岛素抵抗不仅存在于PCOS中，也存在于其它雄激素过剩的疾病中，如先天性肾上腺增生。