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- Solid dispersion solubility 固体分散体
- AIM Preparing the solid dispersion of anethole trithione so as to increase its solubility and dissolution rate. 目的制备茴三硫固体分散体,提高其溶解度和溶出速率。
- Objective:To improve the solubility and in vitro dissolution of isosorbide dinitrate(ISDN) solid dispersion. 目的:采用固体分散技术,提高硝酸异山梨酯在水中的溶解度和体外溶出速率。
- Aim Solid dispersion method was used to increase the solubility and dissolution rates of norfloxacin. 目的利用固体分散体技术,增加诺氟沙星的溶解度和溶出度。
- The solubility of pure drug and HPMC-cisapride solid dispersion was measured with water, SGF and simulated intestinal fluid (SIF). 分别考察纯西沙必利和HPMC-西沙必利固体分散体在水、人工胃液和人工肠液中的溶解度;
- CONCLUSIONS By using solid dispersion methods, the drug was dispersed in PVP in the amorphous form and its solubility was increased. 结论通过固态分散法,药物以无定形分散于载体中,显著改善其溶出。
- Solid dispersion is able to release rapidly as an ameliorated technic. 固体分散体有速释作用,可考虑用固体分散技术改进降酶灵胶囊的制备工艺。
- Objective To optimize the method of preparing Dragon's blood solid dispersion . 目的确定制备龙血竭固体分散体的最佳方法。
- Results The results showed that the solubility of indirubin in solid dispersions prepared by cogrinding method were remarkably enh... 结论共研磨技术能有效地提高难溶药物的溶解度。
- Conclusion The sample of Galactosylglucose and Gliclazide can form solid dispersion by high speed grinding. 结论乳糖和格列齐特一定比例下经高速研磨混合的样品形成了共熔体;
- Abstract:Objective To prepare vinpocetine(VIN) solid dispersion(SD) and improve the dissolution profile of vinpocetine. 目的采用固体分散体技术改善长春西汀(VIN)的体外溶出特性。
- Objective To prepare the etodolac solid dispersion for enhancing its dissolution in vitro. 目的 制备依托度酸固体分散体,以提高依托度酸的溶出度。
- Objective To prepare apigenin (AP) solid dispersion and measure its dissolution in vitro. 目的 制备芹菜素固体分散体,并检测其体外溶出度。
- Conclusion The nifedipine-PEG solid dispersion could accelerate the in vitro drug dissolution. 结论 硝苯地平PEG固体分散体能加快药物的体外溶出速率。
- Conclusion The etodolac-PEG solid dispersion could enhance the drug dissolution in vitro. 结论 依托度酸PEG固体分散体能提高药物的体外溶出度。
- OBJECTIVE To prepare etoposide solid dispersion to enhance the dissolution rate. 目的制备依托泊苷固体分散体,改善依托泊苷的溶出度。
- Methods: The sulfamethoxazole solid dispersion was prepared.The dissolutions of the solid dispersion were detected. 方法:以固体分散技术制备磺胺甲恶唑固体分散体,并测定其体外溶出度。
- OBJECTIVE To study the formation and solubilization mechanism of cefuroxime axetil solid dispersion. 目的探讨头孢呋辛酯-聚维酮固态分散体形成和改善溶出的机制。
- OBJECTIVE To prepare nitrendipine solid dispersion using solvent evaporation-deposition method. 目的:采用溶剂蒸发-沉积法制备尼群地平固体分散体。