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- Tetrodotoxin is one of the strong marine neural toxins which block sodium channels. 河豚毒素是钠离子通道阻断剂,是一种强海洋神经毒剂。
- These anaesthetics block sodium channels and thereby the excitability of all neurons, not just sensory neurons. 这些局麻剂可以阻断钠通道，因此不仅仅阻滞了感觉神经元，也同时阻滞了几乎所有其他神经元的兴奋性。
- Biochemistry: DPX-KN128, the active component, blocks sodium channels in nerve cells. 作用特点主要是阻断害虫神经细胞中的钠通道，导致靶标害虫协调差、麻痹，最终死亡。
- Sodium channels are uniquely found in animal cells, they're not present in plants. 钠离子腺体只在动物细胞里被发现，在植物中则不存在。
- They are lipophilic, so can enter virtually any neuron, where they indiscriminately block sodium channels in the membrane. 它们的亲油性使它们能进入几乎任何神经元，在那里，它们会不加甄别地阻断细胞膜中的钠通道。
- Aim To apply sodium channels isolated and purified from rat brain and rat skelatal muscle sarcolemma to the study conotoxin. 方法3种色谱分离纯化钠通道粗组分,配体结合实验研究钠通道活性及其与桶型芋螺毒素的相互作用。
- Pain-sensing neurons, however, possess a subclass of voltage-gated sodium channels, known as the T TX -resistant type, that do not occur in the CNS. 不过，痛觉受器却拥有一种特别的电位控制钠离子通道，称为河鲀毒（tx）敏感型，而中枢神经系统里并没有这一型。
- Pain-sensing neurons, however, possess a subclass of voltage-gated sodium channels, known as the TTX-resistant type, that do not occur in the CNS. 不过，痛觉受器却拥有一种特别的电位控制钠离子通道，称为河魨毒（tx）敏感型，而中枢神经系统里并没有这一型。
- Some LQTS types stem from faulty or lacking potassium ion channels, while others are due to faulty or lacking sodium channels. 某些类型的LQTS缘于钾离子通道缺陷或缺乏，而其它类型则是由于钠离子通道缺陷或缺乏。
- Voltage gated sodium channels (VGSC) are responsible for the rising phase of the action potential in the membrane of neurons and most electrically excitable cells. 电压门控钠通道(VGSC)在神经元及大多可兴奋性细胞动作电位的形成和传播过程中扮演着极为重要的角色。
- In the field of life sciences, more and more attentions have been paid to the advances in the study of voltage-gated potassium (VGPC), c alcium (VGCC) and sodium channels (VGSC). 电压门控性钾、钙和钠离子通道在生命科学研究领域中受到越来越多的关注。
- Methods: Whole-cell patch clamp technique was used to determine sodium channel cur rent. 方法 :采用全细胞膜片钳技术 ,记录钠通道电流。
- Sodium channel of dorsal root ganglion (DRG) plays an important role in the mechanisms of neuropathic pain. 摘要脊髓背根神经节的钠通道与神经性疼痛的形成有密切的关系。
- Local anesthetics that temporarily inactivate such voltage-gated sodium channels currently treat a variety of different pains, particularly those arising from a trip to the dentist. 目前，有许多不同形式的疼痛（特别是去一趟牙医诊所引起的），可利用局部麻醉剂来止痛，原理就是将这种电位控制型的钠离子通道暂时去活化。
- This review focuses on the relationship between the plasticity of voltage-gated sodium channel subunits and neuropathic pain states. 本文就目前研究较多的几种钠通道亚单位的可塑性与神经性疼痛的关系作一综述。
- It can activate sodium channel,inrease sodium current.it can inrease liber calcium concentration in the myocardial cell. 实验证明：As可激活钙通道，增加钙通道电流 As增加细胞内游离的钙离子浓度 As可激活钠通道，增加钠电流 关键词：龙牙葱木皂苷 培养心肌细胞 L-型钙电流 钠通道 膜片钳 正性肌力作用 Aralosides(As)are omni-glycosides extracted from roots;petiols and skins of Aralia (Miq) seem.
- These included mutations in the sodium channel gene SCN5A, preiously associated with LQTS and other unstable heart rhythm conditions and sudden death. 这其中包括钠通道基因SCN5A的突变，该基因以前发现与LQTS、其他不稳定心律失常以及猝死相关。
- The voltage gated sodium channel is the major target receptor for DDT and pyrethroids, and is the basis of their cross resistance (knockdown resistance). 电压门控的钠通道是拟除虫菊酯 (Pyrethroid)和滴滴涕 (dichloro diphenyl trichloroethane)的共同靶变点 ,是它们产生交互抗性 (击倒抗性 ,Knockdownresistance)的基础。
- To observe the effect of Garlicin on sodium channel in isolated ventricular cell of rats, to find out the mechanism of antiarrhythmia of Garlicin on the ionic channel level. 目的研究大蒜素对豚鼠心室肌细胞膜快钠通道的影响,探讨大蒜素在离子通道水平的抗心律失常作用机制。
- As compared with TTX-R sodium channel, the TTX-S sodium channel was less responsive to Fen exposure, which only led to slowly decay TTX-S sodium tail currents. 氰戊菊酯对TTX-S型钠通道的作用小于TTX-R型，仅表现为对尾电流的关闭有延迟作用。
