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- Quinolones antibacterials have been used widely in the treatment of many kinds of infectious disease in clinic. 喹诺酮类药物在临床中广泛应用于治疗各种感染,但是在其应用中也发现了许多不良反应。
- Objective To improve the synthesis of tetrafluorophthalic acid as an intermediate in preparing quinolone antibacterials. 目的合成喹诺酮类抗菌药中间体四氟邻苯二甲酸,并改进工艺,使之适用于工业化生产。
- Quinolones antibacterials 喹诺酮类药物
- This paper reviews advances in the research of the antibacterials of oxazolidinones and quinolones. 综述了近年来恶唑烷酮类和喹诺酮类抗菌药物的研究进展。
- RESULTS:Penicillins,cephalosporins,macrolides and quinolones took the lead in the total antibacterials used in our hospital. 结果:我院抗菌药物使用主要以青霉素类、头孢菌素类、大环内酯类、氟喹诺酮类为主。
- The quinolone antibacterial has generated considerable interests in controlling microbe infection since it was firstly applied into clinic practice more than 40 years ago. 摘要喹诺酮类抗生素在临床使用已有40多年，它对人类控制微生物感染产生了巨大的作用。
- Structural modification is still popular and important in the area of finding novel quinolone antibacterial agents with more potential activity and broad spectrum. 对喹诺酮类化合物进行进一步的结构修饰,以便获得活性更强,活性谱更广的新喹诺酮类抗菌药,仍是抗感染化疗领域近几年的热点领域之一。
- Quinolones, aminoglycosides drugs and containing enzyme inhibitor complex antibacterials (such as SCF) were batter choices to the infection of Non-fermentative bacteria. 结论喹诺酮类、氨基糖苷类、碳青霉烯类药物以及含酶抑制剂复方型抗菌药物可为治疗非发酵菌感染的首选药物。
- RESULTS:The occurrence of ADR induced by antibacterials of quinolones ranked the first,and the cephalosporins is the second,the penicillin is the third. 结果:由喹诺酮类药物发生的ADR最多,其次是头孢菌素类药物,第三位是青霉素类药物;
- Aim:To study the decarboxylation of quinolones. 目的:研究喹诺酮类化合物脱羧反应。
- The binding characteristics of quinolone antibacterial agent, ofloxacin (OFLX) and ciprofloxacin(CPFX) with catalase(CAT) were studied by fluorescence spectroscopy in aqueous solution. 应用荧光光谱法研究了水溶液中喹诺酮抗菌素氧氟沙星、环丙沙星与过氧化氢酶分子间的结合反应。
- Abstract： The binding characteristics of quinolone antibacterial agent, ofloxacin (OFLX) and ciprofloxacin(CPFX) with catalase(CAT) were studied by fluorescence spectroscopy in aqueous solution. 摘 要： 应用荧光光谱法研究了水溶液中喹诺酮抗菌素氧氟沙星、环丙沙星与过氧化氢酶分子间的结合反应。
- In this paper,the basic configuration,development source,evolution gradation,production and market demand, current situation and so on for quinolone antibacterial agents were summarized in detail. 介绍了喹诺酮类药物基本结构、发展渊源、演变阶段、生产和市场近况,对该药物的最新发展、新品种、应用前景以及有望作为抗癌和抗真菌方面的药物也予简单论述。
- Progresses on the synthesis and classification of the metal complexes based on quinolone antibacterial drugs,their structures,properties as well as their reaching trend in future are reviewed. 本文综述了喹诺酮类抗菌药物金属配合物的合成、分类、结构、性质等方面的研究现状;展望了此类研究的发展趋势.
- Keywords Quinolones antibacterial;Defined Daily Dose;Frequency of drug application;Daily Drug Cost; 关键词喹诺酮类药物;限定日剂量;用药频度;日治疗费用;
- Objective:To study the decarboxylation of quinolones. 目的:研究喹诺酮类化合物脱羧反应。
- The quinolones has been developed to the fourth generation. 喹诺酮类药物目前已经发展到了第四代。
- Objective:To explore ways of the rational use of antibacterials. 目的:探讨抗菌药物合理应用的有效途径。
- Quinolones antibacterial 喹诺酮类药物
- This drug is not for patients who have shown hypersensitivity to quinolones. 对喹诺酮类药物过敏的患者忌用。
