Purpose: High mobility group box-1(HMGB1) was identified as a DNA-binding protein that functions as a cofactor for proper transcriptional regulation in somatic cells.

• 目的： 高迁移率族蛋白-1(HMGB1)被认为是一种DNA结合蛋白，作为辅助因子协助体细胞进行合适的转录调节。