Preiously, Rui and his team hae shown that mice that lack the gene for SH2B1 -- called knockout mice -- become obese, diabetic, and unable to stop eating.

• 试验在两种类型鼠中进行，研究组改变这些鼠遗传信息使它们脑细胞中仅表达单一形式的SH2B1蛋白。