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- The bcr/abl fusion genes were found in patients with negative Philadelphia chromosome. 2例Ph染色体阴性的CGL患者 ,用RT PCR检测出bcr/abl融合基因。
- Before blastic crisis, Philadelphia chromosome (ph) were positive in 18 cases, and negative in 2 patients. 急性变前 ph染色体阳性 18例 ,阴性 2例。
- Philadelphia chromosome was detected in 26 of 28 patients (92.9%)by cytogenetic study. 28例慢粒患者作细胞遗传学检查，26例Ph染色体阳性，2例Ph染色体阴性，阳性率为92.;9%25；
- The Philadelphia chromosome(Ph) was detected in the bone marrow in 49 patients with CML. 检测 49例CML患者骨髓的Ph染色体 ;
- The Philadelphia chromosome is found in more than 90% of patientswith chronic myeloid leukemia(CML) and 30% of patients with acutelymphoblastic leukemia(ALL). 在90%25以上的CML患者和30%25的ALL患者的白血病细胞中存在Ph染色体，这是由9号和22号染色体易位形成的。
- In chronic myelogenous leukemia, a malignant tumor of myeloid stem cells, all cells possess a distinctive (nonrandom) translocation referred to as Philadelphia chromosome. 在慢性髓细胞性白血病，一种髓性干细胞的恶性肿瘤，其所有肿瘤细胞拥有一个特征性的染色体的易位，所涉及的染色体称为费城染色体。
- The Ikaros mutations were not found in 23 adults with CML, confirming the role of this gene in triggering ALL in those with the Philadelphia chromosome. 在23名CML成人患者中并没有发现依卡路斯基因突变，从而证明了这种突变对于在携带费城染色体的人群中触发ALL发挥了重要作用。
- Abstract: Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome positive chronic-phase chronic myeloid leukemia after failure of interferon. 文摘:费城染色体阳性的干扰素治疗失败的处于慢性期的慢性粒细胞白血病患者中的长期存活利益和对imatinib mesylate提升全细胞生成反应及分子反应率的研究。
- Objective To study the bcr/abl fusion gene in chronic myeloid leukemia (CML) cases with Philadelphia chromosome(Ph)negative,and variant Ph translocations and other chromosome anomalies. 目的 检测费城染色体 (Philadelphia chromosome,Ph染色体 )阴性、变异型 Ph染色体及伴有其它染色体异常的慢性粒细胞白血病 (chronic myeloid leukemia,CML)的 bcr/abl融合基因。
- The engraftment analyses included the detection of microsatellite short tandem repeats (STRs), bcr/abl fusion gene, Philadelphia chromosome, HLA-locus analysis, sex chromosome and ABO blood type or blood subtype. 微卫星短串联重复序列(STR)分析、Bcr/Abl融合基因、Ph染色体、HLA位点分析、性染色体及ABO血型等为植活检测指标。
- Among 154 patients with CML who didn?t receive allo-BMT, 142 (92.2%) patients were positive for Philadelphia chromosome detection, 146 (94.8%) patients expressed bcr/abl mRNA, which were consistent in 142 (92.2%) patients. 15 4例未经异基因造血干细胞移植 (allo -PBSCT)的CML患者中 14 2例( 92 2%25 )为Ph染色体阳性 ,14 6例 ( 94 8%25 )表达bcr/ablmRNA ,2种方法结果一致者 14 2份 ( 92 2%25 )。
- Philadelphia chromosome(Ph chromosome) 费城染色体, Ph染色体
- The results showed that 69(68.32%) cases had clonal chromosomal abnormalities and specific abnormalities including Philadelphia chromosome (32.67%), t(4;11)(2.97%), t(11;14) (3.96%) , abnormalities of 8q 24 (2.97%), 6q -(4.96%). 结果显示，69例有染色体异常（占68.;32%25），其中61例为结构异常，特异性异常47例，包括t（9；22），t（4；11），t（11；14）等。
- (Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia)。 这是一种罕见而难治的顽症。
- Philadelphia chromosome positive chronic myeloid leukemia Ph阳性慢性粒细胞白血病
- Keywords Leukemia;granulocytic;chronic;Philadelphia chromosome;Imatinib; 白血病;髓样;慢性;费城染色体;伊马替尼;
- Analysis of Ag-NOR for 198 cases of Philadelphia chromosome positive chronic myeloid leukemia 198例Ph阳性慢性粒细胞白血病Ag-NOR分析
- The position that a given gene occupies on a chromosome. 基因座在一条染色体上某种给定基因所占的位置
- Here is a letter adapted from DEAR ABBY, Philadelphia Bulletin, March9,1973. 这里摘登一封＇亲爱的爱毕＇的回信，刊登在一九七三年三月九日的＇费城公报＇上。
- I am not a beginner in politics in Philadelphia. 我对费拉德尔斐亚市的政治并不是一无所知的人。
