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- Keywords Parkinson s disease model;Rats;Transcranial magnetic stimulation;Motor evoked potentials;Cortical latency;Central conduction; 帕金森病模型;大鼠;经颅磁刺激;运动诱发电位;潜伏期;中枢传导时间;
- Parkinson s disease model 帕金森病模型
- Objective To investigate the role of nitric oxide (NO) in neuronal damage in the rat model of Parkinson ,s disease (PD). 目的 研究一氧化氮 (NO)在帕金森病 (PD)大鼠模型神经损伤中的作用。
- This article reviews the potential effect of glia on Parkinson s disease. 该文就胶质细胞在帕金森病中可能发生的保护和毒性作用及其机制作一综述。
- Objective To establish a rotating model of parkinson s disease with the purpose of evaluating the validity of application of microelectrode-guided pallidotomy in the management of Parkinson s disease. 目的探讨微电极导向在帕金森病苍白球毁损术中的应用价值。方法制作大白鼠帕金森病模型。随机分组,评估治疗效果。结果28只成功的帕金森病模型,微电极导向毁损组10只,右侧苍白球自制针灸针直接毁损组10只,观察组8只。
- Keywords Parkinson s disease;diseases models;animal;ventral pallidum;corpus striatum;microelectrodes;nitric oxide synthase;rats; 帕金森病;疾病模型;动物;苍白球;纹状体;微电极;一氧化氮合酶;大鼠;
- Keywords Alzheimer s disease;disease model;transgenic animals;senescence accelerated mouse;neuronfibrillary tangles;senile plague;amyliod protein; 老年性痴呆;动物模型;转基因动物;早衰小鼠;神经原纤维缠结;老年斑;淀粉样蛋白;
- Methods:Microelectrode recording was used as intraoperative tanget in 31 patients with Parkinson s disease. 目的:探讨微电极记录技术在帕金森病外科治疗中的作用。
- Objective:To discuss the role of microelectrode recording in surgical management of Parkinson s disease. 目的:探讨微电极记录技术在帕金森病外科治疗中的作用。
- Parkinson s disease is a common neurodegenerative disease in middle-aged and elderly people. 帕金森病是中老年人常见的中枢神经系统变性疾病。
- Objective It is to observe the effect of Anti-Park inson granule combin ed with Madopar on Parkinson s disease (PD). 目的观察抗帕颗粒联合美多巴治疗帕金森病的疗效。
- That quells the world’s disease. 它是扑灭世间疾病的灵丹妙药；
- Objective To investigate the clinical and CT manifestations characterized by thepatients of Parkinson,s disease (PD) complicated with depression. 目的探讨帕金森病（PD）伴抑郁症患者CT和临床表现有无特异性。
- Methods 13 patients with Parkinson,s disease were evaluated by using the rating scales of modified Webster and comparing to the baseline values. 方法采用改良Webster评分标准及开放性自身治疗前后对照，评估Pergdide治疗后的疗效及安全性。
- Conclusion Co-transfer of TH and AADC cDNAs into the striatum is a valuable strategy to gene therapy for Parkinson＇s disease. 结论TH和AADC基因的共转导策略，对提高帕金森病基因治疗疗效有重要意义。
- Entacapone,an inhibitor of catechol-O-methyl transferase(COMT),has been adjunctively used to treat Parkinson s disease with levodopa. 恩他卡朋是一种特异性的儿茶酚胺-O-甲基转移酶(COMT)抑制剂。
- When I have days when I struggle, I think about Mr.Grady and how Parkinson’s disease way just a small part of who he was. 在我奋斗之时，我就会想到格瑞迪先生，想到帕金森症只是他生命中多么微不足道的一部分。
- Furthermore, the GABA system in the globus pallidus is involved in the etiology of Parkinson’s disease and regulation of seizures threshold. 已证实，苍白球神经元放电频率的降低及簇状放电的产生与帕金森病运动减少及静山险震颤等症状直接相关。
- The disease model of gene knock-out mouse is of significance in understanding the gene function and pathogenesis of human disease. 通过基因敲除建立的鼠疾病模型，在研究基因功能及人类疑难病症致病机制等方面发挥着前所未有的作用。
- The saccadic movement of patients with Parkinson s disease was abnormal and might be related to the severity of the disease. 帕金森病患者扫视运动存在异常,且可能与疾病的严重程度相关;
