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- PTEN phosphohydrolase PTEN磷酸水解酶
- PTEN might be a target for chemotherapy. PTEN可能是化学疗法的目标。
- BRCA1 inactivates a tumor suppressor gene known as PTEN. BRCA1能够使人体内一种叫PTEN的肿瘤抑制基因失去活性。
- But it was not clear if PTEN regulate VEGF expression in renal carcinoma. 在肾癌中PTEN是否调节VEGF的表达，尚不十分明确。
- Low-expression of PTEN protein may stimulate overexpression of PI3K protein. PTEN表达的缺失可能刺激了PI3K蛋白的强阳性表达。
- Mutation rate of PTEN had a relation with tumor pathological grades. 膀胱癌PTEN的突变率可能与肿瘤的病理学分级有关。
- The 403 amino acid PTEN protein encodes dual specificity protein phosphatases. PTEN为403胺基酸之蛋白质具有双重去磷酸酵素活性，PTEN基因突变常发生于许多末期癌症。
- Role of PTEN in tumorigenesis has been a hotspot of research in tumor domain. 摘要过去，PTEN在肿瘤发生发展中的作用是研究的热点。
- PTEN,VEGF,CD_(34) were determined by immunohistochemistry SABC method. VEGF和PTEN对胃癌患者预后有不同的影响。
- Results:46.67% of cases had expression of DCC and 36.67% of cases had expression of PTEN in the tumor cells. 结果:30例大肠癌中DCC和PTEN蛋白阳性表达率46.;67%25和36
- ObjectiveTo study the effects of wild-type PTEN gene on the invasion ability of glioma c ells. 目的 观察转入野生型 PTEN基因的胶质瘤细胞体外侵袭力改变 ,探索 PTEN基因对胶质瘤细胞影响方式。
- DCC and PTEN expression were correlated with invasion and metastasis of colorectal carcinoma. DCC和PTEN表达与大肠癌浸润转移密切相关。
- Results The PTEN and MGMT protein were all expressed in nucleusr of ductal cellula epithelialis. 结果PTEN与MGMT表达均位于乳腺导管上皮细胞核。
- The mechanism is possibly that dysfunction of hMLH1 gene brig about the down regulation of PTEN gene expression. PTEN和hMLH1蛋白表达也会影响胃癌的部分生物学行为,其机制可能是hMLH1基因功能缺陷导致PTEN基因表达下调。
- These results imply that PTEN may play a role in VSMC remodeling of aorta of SHR. 提示PTEN可能在自发性高血压大属主动脉平滑肌细胞重塑过程中发挥作用。
- PTEN has instructions to produce a protein that stops the uncontrolled cell growth of cancer. PTEN能够产生一种阻止肿瘤细胞无序生长的蛋白质。
- Conclusion: PTEN, VEGF, MVD correlate with the biological characters of gastric cancer and patients prognosis. 结论PTEN、VEGF、MVD的表达与胃癌生物学行为及预后有密切关系。
- Methods Tumor samples from 40 patients with BTCC were analyzed its relationship with PTEN by PCR. 方法采用PCR法观察40例膀胱移行细胞癌标本中PTEN的表达情况。
- Methods: Immunohistochemistry(SP method) was adopted to detect PTEN and PI3K protein expression levels. 方法:采用免疫组织化学SP法检测PTEN与PI3K的蛋白表达。
- To investigate the mutation and methylation of PTEN gene in laryngeal squamous cell carcinoma (LSCC). 摘要目的研究喉鳞状细胞癌（简称鳞癌）蛋白酪氨酸磷酸酶(PTEN)基因突变和启动子甲基化状况。
