PDX-1 contains 3 domains including N-terminal transactivation domain,homeodomain and C-terminal domain,and its amino acid sequence keeps highly conserved among different species.

• 它含有3个结构域，即氨基末端转录活化结构域、同源结构域、羧基末端结构域，并且不同物种间PDX-1的氨基酸序列保持高度的同源性。