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- AIM:To study the safety of intramuscular injection of non viral vector pNMG3 of recombinant human growth hormone gene(hGH). 目的:研究携带重组人生长激素(hGH)基因非病毒载体pNMG3骨骼肌注射方法的急性期安全性。
- Nonviral gene delivery systems are aeternative to the viral ones,but the latter use virus, which is called bacteriophage, as the gene vectors. 非病毒载体基因递送系统是相对于以病毒为载体的基因递送系统的另一种基因递送系统。
- To this end, advances have been made in the areas of cell transplantation and in the development of recombinant viral vectors for gene delivery. 该研究结束时，在细胞移植和为基因传输所进行的重组细胞病毒载体研发这两方面取得了进展。
- A gene that causes the transformation of normal cells into cancerous tumor cells, especially a viral gene that transforms a host cell into a tumor cell. 致癌基因导致正常细胞转变为癌变细胞的基因，尤其是一种把寄主的细胞变为肿瘤细胞的病毒基因
- A gene that causes the transformation of normal cells into cancerous tumor cells,especially a viral gene that transforms a host cell into a tumor cell. 致癌基因，导致正常细胞转变为癌变细胞的基因，尤其是一种把寄主的细胞变为肿瘤细胞的病毒基因。
- Research of MEMS-based microneedles is a very important project in drug and gene delivery. 基于MEMS的微针技术研究是当前药物传输领域中的热点。
- ATF-lys10 mediated gene delivery is uPAR targeting, and the preparation of gene delivery complex is relatively simple. ATF-lys10介导的基因转移具有uPAR靶向性，而且基因转移复合物制备相对比较简单。
- Cristiano M,Richard J.Targeted non-viral gene delivery for cancer gene therapy[J].Front Biosci,1998(3):1161. 郭荣;邹萍;陆华中.;非病毒型纳米载体在基因治疗中的研究现状及展望[J]
- We found that ATF-lys10 mediated uPAR antisense gene delivery could downregulate uPAR protein level as well as adhesion ability to fibronectin. 结果发现，ATF-lys10介导的uPAR反义核酸基因转移可以下调细胞uPAR蛋白水平，并降低细胞与纤连蛋白的粘附能力。
- In the present study, recombinant adeno-associated virus (rAAV) was employed as a gene delivery vector to study glucose regulated insulin gene therapy. 在本研究之中将利用重组腺相关病毒作为基因载体，以研究在体外及体内试验中受葡萄糖调控的胰岛素生产情形。
- Recently,research on polymeric gene delivery vectors aims at developing non/low cytotoxic cationic polymers for safe and efficient gene transfer. 近几年来聚合物基因释放载体的研究主要旨在开发低毒或无毒的阳离子聚合物用于安全有效的基因释放。
- Chitosan nanoparticle has co-permeation and bioadhension,which has a wide development in the research of gene delivery system. 用壳聚糖制备的纳米粒具有助渗作用及生物粘附性,在基因递送载体的研究中具有广阔的发展前景。
- The latent form of a bacteriophage in which the viral genes are incorporated into the bacterial chromosomes without causing disruption of the bacterial cell. 原噬菌体抗菌体的潜在形体，在这种形体中病毒基因和细菌染色体结合，而对细菌细胞不能造成分裂。
- Similarly, the discovery that plants can be "vaccinated" against disease by equipping them with viral genes ought to reduce their reliance on chemical insecticides. 与此类似，给植物注入病毒基因可以使其通过“接种疫苗”增加搞病性，这一发现，可以减少植物对化学杀虫剂的依赖。
- Western blot analysis suggested the decreased cell motility might be attributed to the reduced phosphorylation of focal adhesion kinase (FAK) by PTEN gene delivery. 利用西方墨点法分析可以推测经PTEN基因传送的肝癌细胞移行数目的减少，可能是因降低了FAK磷酸化的缘故所致。
- A latent or immortalizing infection may result from DNA virus infection of a cell that restricts or lacks the machinery for transcribing all the viral genes. 潜伏或永生化感染可以在DNA病毒感染的细胞中引起，因其限制或缺乏病毒基因转录所需的设备材料。
- From the point of practical applications, this kind of surface will be more useful in gene delivery, microfluidic channels, and nonwetting liquid transfer. 以上研究结果使超疏水性表面的性能得到进一步的提高，也必将使其在基因传输、无损失液体输送、微流体等方面具有更广阔的应用前景。
- Gene delivery has become a well used technique both for economic and research purpose and been applied in aquactic organisms, such as fish, shellfish, microalgae, and macroalgae. 摘要:做为经济应用或是基础研究的前提下，基因转殖已经发展成为一个好用的技术工具，用以进行水产生物的特质改良，包括食用的鱼介贝类、微细藻或是大型藻等。
- In gene delivery vectors,non-viral vectors have shown a promising perspective because of their low-toxic,non-immunogenic,non-oncogenic and easy-to-produce properties. 在基因转染载体中,非病毒载体以其低毒性、低免疫原性、低致瘤性及易于制备等优点具有良好的应用前景。
- Second, some reports utilized the baculovirus as a gene delivery vehicle into mammalian cells and did not have any bad effect on the growth of mammalian cell. 因此，本论文中讨论一些影响蛋白质表现量与延长表现的参数如:培养基的更换、重复感染、病毒感染方式。
