Multidrug resistance-associated protein(MRP) plays an important role in the pharmacokinetics of a drug in the body.However,the function of MRP can be affected by probenecid.

• 多药耐药相关蛋白(MRP)载体在药物的体内处置过程中发挥了重要的作用,丙磺舒对MRP有较好的抑制作用。