Methods:The variant of point 519 in LEPR gene was determined by PCR-SSCP method in 100 Northeasten Chinese of Han Nationality.Results:There was no abnormal change in 100 cases during detection.

• 方法:选择无亲缘关系的东北地区汉族人100例,运用PCR-SSCP技术检测瘦素受体基因519位点的变异。