Methods: Male Sprague-Dawlay (SD) rats were subjected to cecal ligation and puncture (CLP, a model of polymicrobial sepsis) or sham operation.

• 方法：取健康成年雄性Sprague-Dawlay(SD)大鼠40只，采用盲肠结扎加穿孔(cecal ligation and puncture，CLP)法复制败血症/感染性休克动物模型。