Methods: Injected phenylephrine into peritoneal cavity of Wistar rats to make VBE model. One group was given 951,and another group was giv- en the mannitol, the water content of gray and white matter was measured with Moisture-Analyzer, respectively.

• 方法：Wistar大鼠腹腔注射苯肾上腺素，制成血管源性脑水肿模型，分注射951和甘露醇组，用远红外线水分分析仪分别测量脑灰、白质水分含量。