Methods 68 patients with refractory schizophrenia were randomly divided into experimental group and control group and respectively treated with Quetiapine and Clozapine for 8 weeks.

• 方法将68例难治性精神分裂症患者随机分为实验组和对照组,分别给予奎硫平、氯氮平治疗8周,用阳性症状与阴性症状量表(PANSS)评价临床疗效,用不良反应症状量表(TESS)评价药物不良反应。