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- MHC class MHC 类别
- Superantigens can bind to a large number of V regions on TCRs and simultaneously also associate with MHC class II molecules on APCs (see figure). 超抗原可以和许多TCR上的V区域结合并同时也和抗原呈现细胞上的第二类MHC分子有关(请参考附图)。
- A typical superantigen may crosslink MHC class II molecules to TCRs on as many as 5-20% of all CD4 T cells (which all share a subset of V domains). 在所有的CD4 T细胞中(这些细胞有同一小组的V范围),其中有5-20%25其TCR上的第二类MHC分子可以和典型的超抗原交互连结。
- The antigenic peptides derived from CT antigens such as MAGE-1[7], MAGE-3[8] and NY-ESO-1[9] have been proven to be elicit CTL responses in the context of MHC class I molecules. 因此,CT抗原无疑是肿瘤免疫治疗的理想靶标。 迄今为止,实验已经证实,来源于多种CT抗原(如MAGE-1,MAGE-3、NY-ESO-1)的抗原肽能够在体外有效地激发特异性的CTL反应。
- Through the T cells receptors (TCRs), CTLs can recognize the MHC class I-associated peptides complex on surface of the antigen presenting cells (APCs) such as malignant cells. CTL通过其T细胞受体特异性识别抗原提呈细胞(antigen-presenting cells,APCs)(如肿瘤细胞)表面的主要组织相容性复合体(major histocompatibility complex, MHC)-I类分子-肽复合物,然后自身得以活化,并最终通过多种机制杀死靶细胞。
- MHC class I-related chain A gene MICA基因
- MHC class II transactivator mutant MHCII类分子反式激活因子突变体
- MHC class Ⅱ transactivator (C Ⅱ TA) MHCⅡ类分子转录激活因子(CⅡTA)
- MHC class Ⅱ transactivator mutant MHCⅡ类分子反式激活因子突变体
- Kindly send us two samples of each class quote for. 报价时,请对每一个等级的各寄两个样品。
- The average age of the boys in this class is fifteen. 本班男生的平均年龄是十五岁。
- Henry is nowhere when it comes to the race for class president. 亨利在竞选级长中被远远抛在后面。
- She got cold feet when asked to recite in class. 当她被叫起来在班上背诵时害怕了。
- She was kept in for an hour for talking in class. 她因上课说话被罚留校一小时。
- The students in our class number thirty. 我班总共有三十名学生。
- I was out and away the handsomest man in the class. 我是当时全班最帅的男子汉。
- Soon I dropped behind the rest of the class. 不久我就落在班上其他同志后面了。
- Pele was in a class of his own as a footballer. 贝利是举世无双的足球健将。
- He always travels first class expense is no object. 他出门总是用头等票--费用不成问题。
- She stood out as the best in the class. 她是班级里最出色的学生。
