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- Objective:To establish the methods for screening the Liuwei Dihuang pills series in the drug testing vehicles. 目的:建立用于药品检测车上快速筛检六味地黄丸系列中成药的快检方法。
- The method of high performance liquid chromatography/electrospray ionization?mass spectrometry (HPLC/ESI?MS) was used for qualitative analysis of Liuwei dihuang pills. 建立了高效液相色谱/电喷雾电离 质谱定性分析六味地黄丸的方法,通过2级质谱识别了其中的9种化学成分。
- RESULTS: Aristolochia acid A content in Aristolochia Fangchi was markedly decreased after intervention by Liuwei dihuang pill. 结果:加入六味地黄丸后,广防己中马兜铃酸A的含量明显降低。
- METHODS: After mixed decoction of Aristolochia Fangchi with Liuwei dihuang pill,the content of Aristolochhia acid A was determined by HPLC and the content change was observed. 方法:广防己与六味地黄丸共煎后,用反相高效液相色谱法测定马兜铃酸A的含量,并观测含量的变化情况。
- Methods 40 male OLETF rats were divided randomly into Liuwei Dihuang Pills group(Group LW) and control group(Group CN) (n=20 per group). 10 male LETO rats were used as normal control group(Group LETO). 方法:OLETF鼠40只,随机分为六味地黄丸干预组和对照组,LETO(long-evanstokushimaotsuka)鼠10只作为正常对照组。
- OBJECTIVE: To study the attenuation action of Liuwei dihuang pill on Aristolochia Fangchi-induced toxicity through determination of the content of Aristolochia acid A in Aristolochia Fangchi. 目的:通过测定六味地黄丸对广防己中马兜铃酸A含量的影响,初步研究广防己的减毒作用。
- Keywords IGT;Liuwei Dihuang pill;intervention observation; 糖耐量低减;六味地黄丸;干预观察;
- Clinical and Pathological Experimental Study on deferring Senile effects of Liuwei Dihuang Pill 六味地黄丸延缓衰老的临床研究及其药理实验研究
- Liuwei Dihuang Pills 六味地黄丸
- Liuwei Dihuang pills (capsules) 六味地黄丸（胶囊）
- Liuwei Dihuang Pill 六味地黄丸
- "Liuwei Dihuang Pill" 六味地黄丸
- Liuwei Dihuang Concentrated Pills 六味地黄浓缩丸
- To improve the stability of nano Liuwei Dihuang particles and anti oxidation of effective components, the glutin microcapsules are prepared. 为提高纳米粒子的稳定性和防止有效成分的氧化, 以明胶作囊材，以纳米六味地黄为芯材，采用喷雾干燥的方法制备了六味地黄明胶微囊。
- Methods:The third method was used to determine the dissolution of Liuwei Dihuang Wan.A HPLC method was established for the determination of dissolution of Loganin and paeonol. 方法:采用溶出度第三法(小杯法)测定六味地黄丸的溶出度,以高效液相色谱法测定其浓度。
- Zhibai Dihuang Pills,a recipe of Chinese medicinal herbs,was used to treat the infertile couples with antisperm and/or antizona pellucida antibodies in their blood serum. 因此设计应用滋阴降火中药知柏地黄丸治疗精子抗体和（或）透明带抗体阳性的免疫性不孕夫妇。
- The nano Liuwei Dihuang can increase the quantity of SOD in blood serum of old rats remarkably.So the effects of fighting against senium can be improved. 小鼠血清对邻苯三酚自氧化速率抑制实验证明，六味地黄纳米化后，有效成分可直接溶出，可显著增加老龄小鼠血清中的SOD，抗衰老的药效得到明显改善。
- Objective:To compare the effect between the membrane separation technique and the traditional method being used to concentrate polysaccharides from Liuwei Dihuang formula. 目的:比较分析膜分离技术与传统工艺对六味地黄多糖活性成分的富集效果。
- Conclusion: Liuwei Dihuang Wan can increase the rat's anti-oxidation ability obviously and have great ability of protect rats from motional tissue injure. 结论：六味地黄丸可明显增强大鼠抗氧化能力，对运动大鼠心肌和骨骼肌有较强的保护作用；
- Liuwei Dihuang Decoction could inhibit thrombosis by repressing platelet aggregation, lowering blood lipid ,Fg and MDA, reducing the secretion of PAI from endothelial cell and increasing the content of t- PA and SOD. 六味地黄汤全方能够抑制模型大鼠血小板聚集率,降低血脂、Fg和MDA,减少内皮细胞分泌PAI,增加t-PA和SOD的水平,抑制血栓形成。
