It is suggested that increased soluble ICAM 1 level in CSF might depict ongoing immunologic activation and ICAM 1 might correlate with the extent of tissue and BBB damage.

• CSF中可溶性ICAM 1水平的升高可能提示正在进行的免疫激活反应 ,并且可溶性ICAM 1与脑组织损害程度及血脑屏障破坏程度密切相关