It has been reported that ischemic tolerance (IT) might be related to excitatory amino acid(EAA), adenosine, immediate early gene(IEG), heat shock protein(HSP) and oncogene B cell lymphoma-2(Bcl-2), etc.

• 目前脑IT的确切机制尚不清楚，认为可能与兴奋性氨基酸(exicitatory amino acid,EAA)、腺苷、即早基因(immediate early gene,IEG)、热休克蛋白(heat shock protein,HSP)及原癌基因B细胞淋巴瘤-2(B cell lymphoma-2，Bc1-2)等因素有关。