Isosorbide mononitrate (5 ISMN) sustained release tablets were prepared by the wet granulation method, using HPMC as skeleton material and octadecanol as retarding agent.

• 采用湿法制粒工艺,以HPMC为骨架材料,十八醇为阻滞剂,制备5-单硝酸异山梨酯缓释片。