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- Evaluation of health-related quality of life in patients with intractable epilepsy. 难治性癫病人生活质量的调查。
- Objective To analyze the effect of epileptogenic zone localization in the surgery for patients with intractable epilepsy. 摘要目的探讨致痫灶综合定位在提高药物难以控制的顽固性癫痫手术疗效中的作用。
- An open trial of Gabapentin as add-on therapy in patients with intractable epilepsy(IE). 加用加巴喷丁治疗难治性癫痫的临床观察
- Conclusion MST is a effective in surgical treatment of intractable epilepsy and can replace conventional methods. 手术方法的改良可明显提高手术效果并减少并发症的产生；
- Conclusion Topiramate is effective on treating the child patients with intractable epilepsy. 结论妥泰作为添加药用于治疗儿童难治性癫痫有效、安全。
- Objective: To study the brain protection of nimodipine in intractable epilepsy patients. 摘要目的探讨尼莫地平对顽固性癫痫病人的脑保护作用。
- Abstract Objective To explore the clinical effectiveness of hemispherectomy on intractable epilepsy. 摘要 目的 研究大脑半球切除术治疗难治性癫痫的近期临床效果。
- Objective To explore the clinical effectiveness of hemispherectomy on intractable epilepsy. 目的研究大脑半球切除术治疗难治性癫痫的近期临床效果。
- Methods 157 Patients with intractable epilepsy were treated with clonazepam,sodium valproate and topiramate. 方法对符合标准的157例难治性癫痫患者给予氯硝西泮、丙戊酸钠、托吡酯。
- Objective To evaluate the efficacy and safety of topiramate as an add on therapy for child intractable epilepsy. 目的评价妥泰治疗儿童难治性癫痫的疗效与安全性。
- MDR1 overe xpression in brain of Patients with medically intractable epilepsy can export AEDs frombrain and contribute to the refectory nature of their seizures. 药物难治性癫痫患者因脑内MDR1的高表达，导致脑内抗癫痫药物（AED）浓度较低而耐药。
- Objective To assess the efficacy and safety of clonazepam as add - on once - daily therapy in patients with intractable epilepsy (IE). 目的 观察顿服氯硝安定添加治疗难治性癫痫(IE)的临床效果与安全性。
- The discovery of the mechanism will be helpful to produce new AEDs and will lead to good result of theraputic treatment of the intractable epilepsy. 因难治性癫痫成因复杂,产生机制仍不十分清楚,难以有针对性地开发新药。
- Methods 17 intractable epilepsy patients underwent intracranial chronic EEG monitoring by using depth and/or subdural grid and strip electrodes. 方法 应用立体定向技术 ,向颅内可疑部位植入深部电极和 /或硬膜下条状电极。 采用DaVinci系统 ,进行长程视频脑电监测 ,记录发作间期及发作期EEG变化 ,确定癫痫起源部位。
- Methods Patients with intractable epilepsy were treated by modified hemispherectomy and clinical effectiveness was followed-up after operation. 方法 对一侧半球病变伴难治性癫痫患者采用改良式半球切除术并随访临床效果。
- Objective To determine the ultrastructural localization of MDR1 and GFAP in the surgically resected brain tissues from intractable epilepsy patients. 目的在电镜水平上观察多药耐药基因蛋白(MDR1蛋白)和胶质原纤维酸性蛋白(GFAP)在难治性癫痫患者脑组织的表达,确定其在细胞超微结构中的定位。
- Objective To explore the curative effect of epileptic surgery under electrocorticogram(ECoG)monitoring in the patients with intractable epilepsy. 目的总结皮质脑电图监测下痫灶切除手术治疗顽固性癫痫的临床疗效。
- Method The localization mode of CT+MRI +EEG+SPECT+ECoG was used in47patients for the sake of increasing the detection rate of the focus of intractable epilepsy. 方法对47例难治性癫痫病人的致痫灶,采用CT+MRI+EEG+单光子发射计算机体层摄影(SPECT)+皮层脑电脑(ECoG)联合检测定位。
- Methods 138 patients with intractable epilepsy involved into this study. CT+MRI+EEG+SPECT+ECoG were provided of localization of the responsible lesion before resection. 方法对138例顽固性癫?病人的致病灶,采用CT+MRI+EEC+单光子发射计算机体层摄影(SPECT)+皮层脑电图(ECoG)联合检测定位。
- Methods EcoG spike foci on the surface of cerebral cortices in 12 cases of intractable epilepsy were removed surgically and studied under electron microscope. 方法 对12例顽固性癫痫患者进行皮质电图监测下手术切除痫灶,电镜下观察痫灶皮质。
