Increased activity of CAMK and the induce rate of Tdp in LVH were suppressed by KN-93. The inactive analog KN-92 had no effect on the activity of CAMK.

• LVH组CaMK的活性高于假手术组(P<0.；05)；KN-93能有效降低肥厚心肌细胞内CaMK活性；而KN-92没有该作用。