In vivo test, DSD effectively prevented neoplasm seeding of B 16 F 10 viable melanoma cells in C 57 BL/6j mouse abdominal cavity and had no obvious toxicity. The efficiency was 70%;

• 小鼠腹腔注入B16?F10 细胞后,按上述三联合液序贯冲洗可预防70%25 的C57 BL/6j小鼠发生腹膜癌病,未见毒副作用。