In this study, we found that over expression of STAT1 in LL2 cells that express constitutively active STAT3 may restore innate immunity but did not inhibit the tumor formation, especially in vivo.

• 在本研究中，我们发现，在表现持续活化态STAT3的肿瘤细胞中，给予持续活化态STAT1的过度表现，可能回复宿主的先天性免疫系统，然而在动物体内肿瘤的生长不会被抑制。