In the present study,a hybrldoma cell line(Ell)was established by fusion of mouse myeloma cells(Sp2/0) with spleen cells from BALB/c mice immunized with HBV antigen purified from human plasma and containing a plenty of HBV Dane particles.

• 以富含Dane颗粒的HBV抗原作免疫原进行研究，选育出一株分泌具有抗HBc及抗HBs双重反应性McAb的杂交瘤细胞株。