In the condition of no light andat the room temperature, DES was mixed with definite quantity succinate anhydridein anhydrous pyridine, stirring 34h and placing in acid circumstance for one night,some light brown oil substances were extracted.

• 避光条件下，以己烯雌酚与一定量的丁二酸酐为原料在室温条件下于无水吡啶中搅拌 34h，酸性环境中静置过夜，有浅棕色油状物析出，过滤，将得到的浅棕色沉淀减压蒸干，得粗产品。