ING1, a recently identified candidate tumor suppressor gene, is downregulated and is deleted and mutated in a variety of primary tumors and established cell lines.

• ING1基因是新近发现的一种抑癌基因，在不同的肿瘤及细胞株中发现ING1基因有不同程度的缺失、突变以及表达异常，对肿瘤的发生发展起促进作用。