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- Objective To observe the effect of vitamin E(VE) supplementation on antioxidation capacity and hippocampus neuron apoptosis in senile female rats. 摘要目的探讨维生素E(VE)对老年雌性大鼠抗氧化作用和海马神经元凋亡调节作用。
- Objective:To observe the effects of Shou erzhi capsule on apoptosis and ultrastructure of hippocampus neuron cell in mice with senile dementia. 目的:观察寿尔智胶囊对老年性痴呆模型小鼠海马神经元细胞凋亡及超微结构的影响。
- Objective: Spin-label electron spin resonance (ESR) spectroscopy technique has been used to investigate the membrane fluidity changes of hippocampus neuron irradiated by EMP. 目的:应用自旋标记电子顺磁共振(Spin label ESR)技术,探讨电磁脉冲对海马细胞膜流动性的影响。
- Objective To investigate the expression of PKC in the hippocampus neuron of TH deficient rats for finding its role on apoptosis of hippocampus in IDD rats and mechanism of learning memony obstacle. 目的研究蛋白激酶C(PKC)在缺碘甲状腺激素不足所致海马神经细胞凋亡的表达和学习记忆低下可能的机制。
- DPCPX can increase BDNF protein expression in the granular cells of rat hippocampus,and induce function enhancement of ER in rat hippocampus neurons. DPCPX可促进大鼠海马颗粒细胞内BDNF蛋白表达和诱导海马神经元内质网功能增强。
- The firing pattern of single hippocampal neuron was obviously modulated both by the ATRC and by the ATPDH. ATRC和ATRDH均能明显调制单个HPC神经元的紧张式放电成为节律性爆发式放电;
- Aim: To study the effect of fetus hypobaric hypoxia on the number and channel character of NMDA receptor of hippocampus neurons. 目的:观察低压低氧环境对胎鼠海马神经元NMDA受体数目和通道特性的影响。
- The result showed that the numbers of hippocampal neuron decreased and the contents of NO increased in burn rats. 烧伤大鼠血清可引起培养的海马神经元细胞存活率下降,培养液中NO含量升高;
- Objective To study the effect of gingkgo leaf on the ultrastructure of hippocampal neuron in mouse and its anti-consenescence effect. 目的研究银杏叶提取物对小鼠海马神经元超微结构的影响及抗衰老作用。
- Hippocampal neuron survival was assessed by MTT method and hippocampal neuron mitochondrial membrance potential (MMP) was evaluated by fluorescence microscope and flow cytometry. 采用荧光显微镜及流式细胞仪观察和检测海马神经元的线粒体膜电位变化。
- Seizures of 16 rats were induced by Kainic acid, and changes in discharge activity of hippocampal neuron, ECoG and behavior of epileptic rats were observed after VNS. 16只大鼠皮下注射海人藻酸致痫。 经迷走神经刺激术观察致痫大鼠海马神经元放电活动、大脑皮质电图及行为学变化。
- Objective To study the effect and mechanism of N-acetylcysteine (NAC) on hippocampal neuron death caused by glutamate at different concentration, and evaluate its toxicity. 目的 观察N-乙酰半胱氨酸(N-acetylcysteine,NAC)对不同浓度谷氨酸(Glutamte,Glu)诱导海马神经元损伤的影响,探讨其作用机制,评价毒性作用。
- Method In vitro: primary hippocampus neurons were cultured using embryo rat brains, the MTT and the activity of LDH were assayed and the pathology was observed, so as to study the protection of Tet from excitotoxicity induced by quinolinic acid(QA). 方法:离体实验:采用海马神经元原代培养,检测培养神经元的MTT、 LDH活性,并观察其病理形态学改变,来研究Tet对QA损伤的海马神经元的保护作用。
- Method:In vitro: primary hippocampus neurons were cultured using embryo rat brains, the MTT and the activity of LDH were assayed and thepathology was observed, so as to study the protection of Cin from excitotoxicity induced by quinolinic acid(QA). 方法:采用海马神经元原代培养,检测培养神经元的MTT、 LDH活性,并观察其病理形态学改变,来研究Cin对QA损伤的海马神经元是否有保护作用,利用海马神经元损伤细胞模型,通过检测各组神经元的MDA含量、NOS活性、细胞内游离Ca2+浓度及细胞外几种兴奋性氨基酸和抑制性氨基酸含量的变化情况来探讨Cin对QA损伤海马神经元保护作用的相关作用因素。
- The probable mechanisms are that chronic antidepressants treatment reduced hippocampus neurons injury by the influence on monoamine neurotransmitter and nerve growth factor expression. 其机制可能是长期的抗抑郁药治疗促进了脑内单胺递质和神经生长因子的表达。
- Keywords morphine;hippocampus neuron;cholecystokinin (CCK);receptor; 吗啡;海马神经元;胆囊收缩素;受体;
- VNS could remarkably suppress the seizure of epileptic animals, and epileptiform ECoG, epileptiform discharges of hippocampal neuron and behavior significantly changed with the total effective rate greater than 50%. 迷走神经刺激可以阻抑各组致痫动物的痫性发作,痫性皮质电图、海马神经元电活动及行为学表现均呈现显著的变化,总有效率达50%25以上。
- The expression of IR,IRS - 1 decreased in the hippocampal neuron in CPR rats,and early administration of neurotrophic factor-APP17 peptide could recover the expression of IR,IRS-1 to or approximately to the normal level. 心肺复苏大鼠海马神经元IR、IRS-1表达降低,复苏早期给予APP17肽干预可使其表达恢复正常或接近正常。
- Objective:To study the ultrastructure of cultured hippocampal neurons in vitro. 目的:研究体外培养海马神经元的表面超微结构。
- Whole - cell recordings of hypoxia injury of hippocampus neuron in newborn rat brain slice 缺氧性损伤时新生鼠脑离体薄片海马回神经元全细胞膜片钳记录