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- Objective To investigate the effect of tetradrine(Tet) on the contend of MDA,the activity of NOS and Na~+-K~+-ATP,Ca~(2+)-Mg~(2+)-ATP of primary hippocampi neurons cocultured with quinolinic acid(QA). 目的探讨粉防己碱(Tet)对喹啉酸(QA)诱导损伤的原代海马神经元丙二醛(MDA)、一氧化氮合酶(NOS)及Na+-K+-ATP酶和Ca2+-Mg2+-ATP酶的影响。
- Methods Hippocampi neurons were cultured,the contend of MDA and the activity of NOS and Na~+-K~+-ATP,Ca~(2+)-Mg~(2+)-ATP of which were assayed through biochemical methods after damaged by QA,and the effect of Tet on these indexes were observed. 方法采用海马神经元原代培养,生化法检测QA损伤后海马神经元MDA含量、NOS及Na+-K+-ATP酶和Ca2+-Mg2+-ATP酶活性并观察Tet对损伤后海马神经元上述指标的影响。
- Objective:To study the ultrastructure of cultured hippocampal neurons in vitro. 目的:研究体外培养海马神经元的表面超微结构。
- Keywords Tetradrine;Quinolinic acid;Hippocampi neurons;Apoptosis; 关键词粉防己碱;喹啉酸;海马神经元;凋亡;
- Although learning must occur if newborn hippocampal neurons are to survive, not all types of learning work. 虽然必须有学习的刺激才能让新生神经元存活，但并不是所有学习类型都有效。
- In addition, the method using CLSM to investigate the nucleic acidic content of hippocampal neurons was also studied. 此外，本研究还对使用激光扫描共聚焦显微镜测定海马脑片内神经元核酸含量的方法进行了探索。
- Methods The interspike interval (ISI) sequences of discharge of the hippocampal neurons were analyzed. 方法分析长时间顺序记录的猕猴海马神经元自发放电的动作电位间期序列(ISI)。
- Objective To study the early radiobiological response of Gamma knife to the cultured hippocampal neurons in vitro. 目的研究伽玛刀对体外培养的海马神经元的早期放射生物学反应。
- Nimodipine may have protective effects on degenerative hippocampal neurons induced by acute lead poisoning. 尼莫地平可能具有抗急性铅染毒海马神经元损伤的作用。
- Conclusions The method for the primary culture of hippocampal neurons is a good method for t... 结论本方法适合一般实验室开展海马神经细胞培养。
- Inhibition of Glutamatergic Activation of Extracellular Signal-regulated Protein Kinases in Hippocampal Neurons by the Intravenous Anesthetic Propofol. 静脉麻醉药物异丙酚抑制海马神经细胞的谷氨酸能激活的细胞外信号调节激酶。
- The alteration of the brian with increasing age may be based on the changes of synaptic interface parameters in the hippocampal neurons of mice. 小鼠海马CA_1区神经元突触界面结构参数的变化可能是海马增龄性改变的基础。
- Objective To study topiramate's neuroprotection on primary cultured hippocampal neurons which were injuried by glutamate and its mechanism. 摘要目的探讨托吡酯对离体大鼠海马神经元谷氨酸损伤的保护作用及其机制。
- DPCPX can increase BDNF protein expression in the granular cells of rat hippocampus,and induce function enhancement of ER in rat hippocampus neurons. DPCPX可促进大鼠海马颗粒细胞内BDNF蛋白表达和诱导海马神经元内质网功能增强。
- The firing pattern of single hippocampal neuron was obviously modulated both by the ATRC and by the ATPDH. ATRC和ATRDH均能明显调制单个HPC神经元的紧张式放电成为节律性爆发式放电；
- Conclusions The results suggest that NMDA-receptor-channels in rat hippocampal neurons are activated significantly during hypoxia. 结论缺氧使海马神经元NMDA受体通道电流幅值升高。
- Aim: To study the effect of fetus hypobaric hypoxia on the number and channel character of NMDA receptor of hippocampus neurons. 目的:观察低压低氧环境对胎鼠海马神经元NMDA受体数目和通道特性的影响。
- Objective: To investigate the effect of pyrroloquiniline quinone(PQQ) on the growth of hippocampal neurons cultured in vitro. 目的:探讨吡咯喹啉醌(PQQ)对培养海马神经元的促生长作用。
- The result showed that the numbers of hippocampal neuron decreased and the contents of NO increased in burn rats. 烧伤大鼠血清可引起培养的海马神经元细胞存活率下降,培养液中NO含量升高;
- Purpose To observe real-time changes of intracellular calcium arose from glutamate and taurine in cultured rat hippocampal neurons. 目的观察抑制性氨基酸牛磺酸对兴奋性氨基酸谷氨酸所致胞内钙超载的影响。
